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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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A Study of Melphalan With or Without Siltuximab in People With Multiple Myeloma Having an Autologous Stem Cell Transplant

for
Multiple Myeloma
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 60+

Code: NCT06679829

Phase 2, Recruiting

Gemcitabine & Nab-Paclitaxel in Pancreatic Adenocarcinoma With Positive Peritoneal Cytology

for
Pancreatic Adenocarcinoma
Location: Seattle WA
Sponsor: Benaroya Research Institute

Sex: All

Age: 18+

Code: NCT03703089

Phase 1, Recruiting

In Vivo Metabolic Profiling of CLL (Chronic Lymphocytic Leukemia)

for
Chronic Lymphocytic Leukemia
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18+

Code: NCT04785989

Recruiting

Study of HER2 Directed Dendritic Cell (DC1) Vaccine + Weekly Paclitaxel, Trastuzumab & Pertuzumab

for
HER2-positive Breast Cancer
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT05325632

Phase 2, Recruiting

Cultured Circulating Tumor Cells in Prostate and Other Cancers

for
Prostate Cancer
Location: Las Vegas NV
Sponsor: Oscar Goodman, Jr.

Sex: All

Age: 18+

Code: NCT02123862

Recruiting

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Phase Ib Study of CBP-1019 in Combination With FOLFOX +/- Bevacizumab, Pembrolizumab, or Enzalutamide for Metastatic TRPV6-overexpressing Solid Tumors of Epithelial Origin

for
Solid Tumor
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06576037

Phase 1, Recruiting

Intravesical Photodynamic Therapy ("PDT") in BCG-Unresponsive/Intolerant Non-Muscle Invasive Bladder Cancer ("NMIBC") Patients

for
Non-Muscle Invasive Bladder Cancer ("NMIBC") Unresponsive/Intolerant to BCG,
Location: Halifax, Montreal, Syracuse NY, Myrtle Beach SC,
Sponsor: Theralase® Technologies Inc.

Sex: All

Age: 18+

Code: NCT03945162

Phase 2, Recruiting

Oral Minoxidil for the Treatment of Recurrent Platinum Resistant Epithelial Ovarian Cancer

for
Ovarian Cancer
Location: Maywood IL
Sponsor: Loyola University

Sex: Female

Age: 18 - 70+

Code: NCT05272462

Phase 2, Recruiting

Biology of Young Lung Cancer Study: The YOUNG LUNG Study

for
Non Small Cell Lung Cancer, Small Cell Lung Carcinoma,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 15+

Code: NCT05265429

Recruiting

Intra-arterial Perfusion in Interventional Radiology

for
Hepatocellular Carcinoma
Location: Palo Alto CA
Sponsor: Palo Alto Veterans Institute for Research

Sex: All

Age: 18+

Code: NCT05458791

Recruiting

Novel Subtypes of Polycystic Ovary Syndrome

for
Polycystic Ovary Syndrome
Location: Hershey PA
Sponsor: Shandong University

Sex: Female

Age: 18 - 45

Code: NCT06124391

Recruiting

Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

for
Myeloid Malignancy, Inherited Bone Marrow Failure Syndrome,
Location: Jacksonville FL, Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT02958462

Recruiting

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

for
Non Small Cell Lung Cancer
Location: Westbrook ME, Stony Brook NY, Stamford CT,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06312137

Phase 3, Recruiting

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

for
Carcinoma, Non-Small-Cell Lung,
Location: Montreal, Fairfax VA, Toronto, Cleveland OH, Detroit MI,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT05208762

Phase 1, Recruiting

Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia

for
High Risk Myelodysplastic Syndrome,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03214562

Phase 1, Phase 2, Recruiting

Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease

for
Pediatric ALL, Congenital Heart Disease, Heart Transplantation
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 10 - 18

Code: NCT06325280

Recruiting

Comparing Operative vs Non Operative Treatment for Pilonidal Disease

for
Pilonidal Disease
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 8+

Code: NCT05439291

Recruiting

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

for
Neuroblastoma, Ewing Sarcoma, Osteosarcoma, Rhabdomyosarcoma,
Location: Providence RI, Hartford CT, Hackensack NJ, Montreal,
Sponsor: Milton S. Hershey Medical Center

Sex: All

Age: 0 - 30

Code: NCT06541262

Phase 1, Phase 2, Recruiting

Dose-escalated Adaptive Radiotherapy of Thoracic Disease for Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Edmonton
Sponsor: AHS Cancer Control Alberta

Sex: All

Age: 18+

Code: NCT04952480

Phase 2, Recruiting

Intraoperative Radiation Therapy for Resectable Pancreas Cancer

for
Pancreas Cancer
Location: Maywood IL
Sponsor: Loyola University

Sex: All

Age: 18+

Code: NCT02599662

Phase 1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer