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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

HCMT/MM2401: Ph2 Study of Selinexor + Bispecific Antibody for RRMM

for
Multiple Myeloma in Relapse, Multiple Myeloma, Refractory
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06822972

Phase2, Recruiting
Active & Responsive

The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV

for
HIV, Depression in Adults, Insulin Resistance,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT07226128

Recruiting
Active & Responsive

Cold and Compression After Rotator Cuff Repair (RCR)

for
High-grade Partial or Full Thickness Rotator Cuff Tears
Location: Kenner LA
Sponsor: Ochsner Health System

Sex: All

Age: 35+

Code: NCT07516327

Recruiting
Active & Responsive

Open-label Study of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH)

for
Secondary Hemophagocytic Lymphohistiocytosis (sHLH)
Location: New York NY, Philadelphia PA, Washington D.C. DC,
Sponsor: Electra Therapeutics Inc.

Sex: All

Age: 6+

Code: NCT05416307

Phase2, Phase3, Recruiting
Active & Responsive

Replacing Bone Marrow Diagnostics With Peripheral Blood Analysis in Cytopenia Patients

for
Cytopenia, MDS
Location: Miami FL, San Diego CA
Sponsor: Weizmann Institute of Science

Sex: All

Age: 18+

Code: NCT07081087

Recruiting

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Active & Responsive

Study to Evaluate the Safety and Efficacy of the 10 GE Xenokidney in Patients With ESRD

for
ESRD (End-Stage Renal Disease), Kidney Transplantation,
Location: New York NY, Chicago IL
Sponsor: United Therapeutics

Sex: All

Age: 40 - 70

Code: NCT06878560

Phase1, Phase2, Recruiting
Active & Responsive

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for
Glioma, Astrocytoma, Grade IV, IDH1-mutant Glioma,
Location: Boston MA, New Haven CT, New York NY, New Brunswick NJ,
Sponsor: Nuvation Bio Inc.

Sex: All

Age: 18+

Code: NCT05303519

Phase3, Recruiting
Active & Responsive

Prepping for The Talk: Helping Trusted Adults and Youth Talk About Sexual Health

for
HIV Prevention, Sexual Health
Location: Providence RI
Sponsor: Rhode Island Hospital

Sex: Male

Age: 14 - 17

Code: NCT07011563

Recruiting
Active & Responsive

Leg Heating in Pregnant Women With Obesity

for
High-risk Pregnancy
Location: Dallas TX
Sponsor: University of Texas Southwestern Medical Center

Sex: Female

Age: 18 - 45

Code: NCT06932250

Recruiting
Active & Responsive

A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

for
Pancreatic Ductal Adenocarcinoma
Location: Boston MA, New York NY, Durham NC
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07024615

Phase1, Recruiting
Active & Responsive

A First-in-Human Study to Evaluate Implantable Iontophoresis Chemotherapy Delivery Device With Gemcitabine Once Weekly or Twice Weekly in Participants With Pancreatic Cancer

for
Pancreatic Adenocarcinoma Non-resectable
Location: Morgantown WV, Ann Arbor MI
Sponsor: Continuity Biosciences, LLC

Sex: All

Age: 18+

Code: NCT07481383

Phase1, Recruiting
Active & Responsive

Topical Ketotifen 0.25% for Secondary Vestibulodynia

for
Provoked Vestibulodynia, Secondary Provoked Vestibulodynia,
Location: Washington D.C. DC, Tampa FL, New York NY
Sponsor: Center for Vulvovaginal Disorders

Sex: Female

Age: 18+

Code: NCT07257029

Phase2, Recruiting
Active & Responsive

A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

for
Geographic Atrophy Secondary to Age-related Macular Degeneration,
Location: Boston MA, New York NY, Toms River NJ, Philadelphia PA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 50+

Code: NCT07441642

Phase2, Recruiting
Active & Responsive

Use of [18F] Fluoroethyl-L-tyrosine PET/MRI for Identifying Small Functional Pituitary Adenomas

for
Pituitary Adenoma
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 70+

Code: NCT07456878

Phase1, Recruiting
Active & Responsive

Tegavivint With Gemcitabine in Patients With Relapsed or Refractory Osteosarcoma

for
Osteosarcoma Recurrent, Osteosarcoma in Children,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 1 - 30

Code: NCT07144254

Phase1, Recruiting
Active & Responsive

Using Microbiome to Predict Durvalumab Toxicity in Post- Concurrent Chemoradiation Therapy (CCRT) NSCLC Patients

for
NSCLC, Stage III, Locally Advanced Lung Carcinoma
Location: Kansas City KS
Sponsor: Jun Zhang, MD, PhD

Sex: All

Age: 18+

Code: NCT04680377

Recruiting
Active & Responsive

Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma

for
Glioma, Malignant
Location: Durham NC
Sponsor: Darell Bigner

Sex: All

Age: 18+

Code: NCT04547777

Phase1, Recruiting
Active & Responsive

Durvalumab and Tremelimumab in Combination With Chemotherapy in HIV-infected Patients With Non-small Cell Lung Cancer

for
Carcinoma, Non-Small Cell Lung
Location: Baltimore MD, Washington D.C. DC
Sponsor: Georgetown University

Sex: All

Age: 18+

Code: NCT04499053

Phase2, Recruiting
Active & Responsive

Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome

for
Myelodysplastic Syndromes
Location: The Bronx NY, Baltimore MD, Miami FL, Orlando FL,
Sponsor: Syntrix Biosystems, Inc.

Sex: All

Age: 18+

Code: NCT04245397

Phase1, Recruiting
Active & Responsive

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for
Advanced Melanoma
Location: Boston MA, Lake Success NY, New York NY,
Sponsor: Immunocore Ltd

Sex: All

Age: 18+

Code: NCT05549297

Phase3, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer