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Oncology Clinical Trials

Browse 8,120 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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Active & Responsive

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

for
Colorectal Cancer, Pancreatic Ductal Adenocarcinoma,
Location: Mineola NY, New York NY, Montreal, Ottawa, Roanoke VA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06428409

Phase 1, Phase 2, Recruiting
Active & Responsive

Evaluation of the Neurologic Assessment in Pediatric Neuro-Oncology (pNANO)

for
Pediatric Brain Tumor, Pediatric Spine Tumor
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 1 - 17

Code: NCT06981156

Recruiting
Active & Responsive

Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL

for
CLL/SLL
Location: Boston MA, Charlotte NC, Jacksonville FL, Canton OH,
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18 - 70+

Code: NCT04215809

Phase 1, Recruiting
Active & Responsive

Mood Alterations in the Patients With Non-Muscle Invasive Bladder Cancer Treated With BCG

for
Non-Muscle Invasive Bladder Cancer
Location: Washington D.C. DC
Sponsor: Johns Hopkins University

Sex: All

Age: 18+

Code: NCT05672615

Recruiting
Active & Responsive

EUS RFA for Treatment of Pancreatic Ductal Adenocarcinoma (PDAC)

for
Pancreatic Cancer
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT05723107

Phase 1, Recruiting

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Active & Responsive

Oral Azacitidine in Transplant-Eligible Patients With Acute Myeloid Leukemia (AML) Suffering From Health-Inequality

for
Acute Myeloid Leukemia
Location: Richmond VA
Sponsor: Virginia Commonwealth University

Sex: All

Age: 18+

Code: NCT06370000

Recruiting
Active & Responsive

Barrigel® PPRT (Post-Prostatectomy Radiation Therapy) Trial

for
Prostate Cancer
Location: Boston MA, Clifton NJ, Richmond VA, Boca Raton FL,
Sponsor: Palette Life Sciences, Inc.

Sex: Male

Age: 18+

Code: NCT06496256

Recruiting
Active & Responsive

Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy

for
Gastrointestinal Cancer
Location: Detroit MI
Sponsor: Henry Ford Health System

Sex: All

Age: 18+

Code: NCT06065371

Phase 1, Recruiting
Active & Responsive

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

for
Extensive Stage-small Cell Lung Cancer
Location: Lebanon NH, Mineola NY, New York NY, Hackensack NJ,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT06362252

Phase 1, Phase 2, Recruiting
Active & Responsive

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

for
Prostate Cancer, Prostatic Neoplasms
Location: Boston MA, New Haven CT, West Haven CT, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: Male

Age: 18+

Code: NCT06925737

Phase 3, Recruiting
Active & Responsive

ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer

for
Prostate Cancer
Location: New York NY
Sponsor: NYU Langone Health

Sex: Male

Age: 18+

Code: NCT06397703

Phase 2, Recruiting
Active & Responsive

Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma

for
Neuroblastoma, Refractory Neuroblastoma, Relapsed Neuroblastoma,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 1+

Code: NCT05400603

Phase 1, Recruiting
Active & Responsive

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for
Colorectal Cancer
Location: Pennington NJ, Philadelphia PA, Newark DE, Baltimore MD,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06562543

Recruiting
Active & Responsive

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

for
Non-small Cell Lung Cancer, NSCLC
Location: Hackensack NJ, Trois-Rivieres, Pennington NJ, Montreal,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06422143

Phase 3, Recruiting
Active & Responsive

Study of Cryoablation and Nirogacestat for Desmoid Tumor

for
Desmoid Tumor
Location: Palo Alto CA
Sponsor: Nam Bui

Sex: All

Age: 18+

Code: NCT05949099

Phase 2, Recruiting
Active & Responsive

Study of STM-416p Administered to Patients Undergoing Radical Prostatectomy

for
Prostate Cancer
Location: Gainesville FL, Tucson AZ
Sponsor: SURGE Therapeutics

Sex: Male

Age: 18+

Code: NCT06450106

Phase 1, Recruiting
Active & Responsive

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

for
Non-small Cell Lung Cancer, Histiocytic Neoplasm, Histiocytosis,
Location: Boston MA, New Haven CT, New York NY, Fairfax VA,
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 18+

Code: NCT05786924

Phase 1, Phase 2, Recruiting
Active & Responsive

FUS Etoposide for DMG

for
Diffuse Intrinsic Pontine Glioma,
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 4 - 21

Code: NCT05762419

Phase 1, Recruiting
Active & Responsive

MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

for
Metastatic Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06648434

Phase 1, Recruiting
Active & Responsive

Regional or Extend LymphAdenectomy During Resection of Intrahepatic Cholangiocarcinoma

for
Intrahepatic Cholangiocarcinoma
Location: Baltimore MD
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Sex: All

Age: 18 - 70+

Code: NCT04078230

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer