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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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1
New

External Beam and Radioligand Radiotherapy for mCRPC

for
Prostate Cancer Metastatic Castration-Resistant
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: Male

Age: 0+

Code: NCT07354594

Phase2, Recruiting
New

Assessing PI3K Gamma Inhibition With Azacitidine, Venetoclax and Eganelisib in Patients With Acute Myeloid Leukemia

for
Leukemia, Myeloid, Leukemia, Acute Myeloid Leukemia,
Location: Boston MA
Sponsor: Jacqueline Garcia, MD

Sex: All

Age: 18 - 70+

Code: NCT07439211

Phase1, Recruiting
New

BRIDGE-SIC Efficacy Trial

for
Cancer
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07735442

Recruiting
New

A Ph II Study of the TheraBionic P1 Device in Subjects With Hormone Positive Breast Cancer

for
HER2-negative Breast Cancer, Hormone Receptor Positive Tumor,
Location: Port Huron MI, Mount Clemens MI, Detroit MI, Lapeer MI,
Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All

Age: 22+

Code: NCT07227831

Recruiting
New

Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative Radiotherapy for the Treatment of Early-Stage Non-Small Cell Lung Cancer

for
Early Stage Lung Non-Small Cell Carcinoma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT07718672

Phase2, Recruiting

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New

Study of Pembrolizumab + Pemetrexed + Platinum Chemotherapy With or Without Zoldonrasib as First Line Treatment in Metastatic Non-squamous RAS G12D-Mutated NSCLC

for
NSCLC, Non-small Cell Lung Cancer,
Location: Plantation FL
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07777822

Phase3, Recruiting
New

A Study of Romosozumab in People With Breast Cancer and Osteoporosis

for
Breast Cancer, Metastatic Breast Cancer (MBC)
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 18+

Code: NCT07776613

Phase2, Recruiting
New

Acupuncture and Exercise for EV-Pembro-Induced Peripheral Neuropathy

for
Metastatic Bladder Cancer, Peripheral Neuropathy,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT07548476

Recruiting
New

Understanding New Cachexia Subtypes Through Observational Epidemiological Research

for
Advanced Colorectal Carcinoma,
Location: Pleasanton CA
Sponsor: Kaiser Permanente

Sex: All

Age: 18+

Code: NCT07776353

Recruiting
New

Indirect Calorimetry-Guided Parenteral Nutrition Prescribing in Oncology Patients

for
Malnutitrion, Cancer
Location: Philadelphia PA
Sponsor: Fox Chase Cancer Center

Sex: All

Age: 18+

Code: NCT07776704

Recruiting
New

A Study to Investigate Velzatinib Compared With Imatinib in Adult Participants With Previously Untreated Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (StrateGIST Frontline)

for
Gastrointestinal Stromal Neoplasms
Location: Toronto, Canton OH, Knoxville TN, Omaha NE
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT07585266

Phase3, Recruiting
New

To Access the Safety and Effects of Intravenous Administration of VIR-5818 Alone and in Combination With Pembrolizumab in Adult Participants With Locally Advanced or Metastatic HER2-Expressing Cancers

for
Locally Advanced or Metastatic HER2-Expressing Cancers
Location: Duarte CA
Sponsor: Vir Biotechnology, Inc.

Sex: All

Age: 18+

Code: NCT05356741

Phase1, Phase2, Recruiting
New

Pemefolacianine for IMI of Lung Cancer

for
Lung Cancer (Locally Advanced or Metastatic)
Location: Philadelphia PA
Sponsor: Sunil Singhal

Sex: All

Age: 18+

Code: NCT07772895

Phase1, Recruiting
New

Whole Body Metabolic Activity as a Reflection of Tumor Metabolic Dysregulation and a Predictor of Treatment Response in Ovarian Cancer

for
Epithelial Ovarian Cancer
Location: Knoxville TN
Sponsor: University of Tennessee Graduate School of Medicine

Sex: Female

Age: 18+

Code: NCT07764133

Recruiting
New

Luminal Bladder Cancer Effective Response to Neoadjuvant Chemotherapy (LUMBER-NAC)

for
Bladder Cancer
Location: New Brunswick NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18 - 70+

Code: NCT07762586

Phase2, Recruiting
New

Evaluating the Impact of CONNECT in a Multilingual Population

for
Smoking Cessation,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 50 - 70+

Code: NCT07111936

Recruiting
New

M-2018-334 in Hematological Malignancies

for
Hematological Malignancies
Location: Duarte CA
Sponsor: Miltenyi Biomedicine GmbH

Sex: All

Age: 18 - 70+

Code: NCT06225050

Recruiting
New

Effectiveness of an eHealth Intervention for Uptake of Cervical Cancer Screening in Hispanic Women

for
Cervical Cancer Screening
Location: Tallahassee FL
Sponsor: Florida A&M University

Sex: Female

Age: 21 - 65

Code: NCT06741241

Recruiting
New

Collection of CSF Samples From Participants With Metastatic Triple Negative Breast Cancer (TNBC) and HER2+ Breast Cancer With no Prior History Nor Active Radiographically Detectable Brain Metastases

for
Breast Cancer, Breast Carcinoma, Cancer of the Breast,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT07619534

Recruiting
New

A Study to Compare the Steady-State Bioavailability of Injectable Letrozole SIE and Oral Letrozole in Post-Menopausal Women With Hormone Receptor Positive Early Breast Cancer

for
Hormone Receptor Positive Early Breast Cancer
Location: Margate FL, Beverly Hills CA
Sponsor: Rovi Pharmaceuticals Laboratories

Sex: Female

Age: 18 - 70+

Code: NCT07401381

Phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer