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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

for
Rectal Cancer
Location: St. John's, Gloucester MA, Beverly MA, Burlington MA,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT06205485

Phase3, Recruiting

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

for
Hormone Receptor Positive HER-2 Negative Breast Cancer,
Location: Boston MA, Horsham PA, Philadelphia PA, Richmond VA,
Sponsor: Puma Biotechnology, Inc.

Sex: All

Age: 18+

Code: NCT06369285

Phase2, Recruiting

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC

for
Metastatic Colorectal Cancer, Hepatocellular Carcinoma
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06553885

Phase2, Recruiting

Avapritinib With Decitabine in Patients With SM-AHN

for
Systemic Mastocytosis With an Associated Hematologic Neoplasm
Location: Tampa FL, Salt Lake City UT
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT06327685

Phase1, Recruiting

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

for
Leukemia, Lymphoma, Myeloma, Myelodysplastic Syndromes,
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18+

Code: NCT05745285

Recruiting

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A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors

for
Squamous Non-small-cell Lung Cancer,
Location: New Haven CT, Hackensack NJ, Fairfax VA, Louisville KY,
Sponsor: Alentis Therapeutics AG

Sex: All

Age: 18+

Code: NCT06747585

Phase1, Phase2, Recruiting

The HIMALAYAS Trial and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Study: A Multicentre Randomized Controlled Trial

for
Heart Failure, Cardiotoxicity, Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18 - 45

Code: NCT05023785

Recruiting

New MRI Biomarkers in Head and Neck Cancers

for
Head and Neck Cancer, Thyroid Cancer
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT03483337

Recruiting

DNA Repair Activity in the Skin of Day and Night Shift Workers

for
Skin Cancer
Location: Fairborn OH
Sponsor: Wright State University

Sex: All

Age: 18 - 40

Code: NCT04122456

Recruiting

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

for
Leukemia, High Risk Acute Lymphoblastic Leukemia,
Location: Philadelphia PA
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 0 - 25

Code: NCT06839456

Phase1, Phase2, Recruiting

Microendoscopic EI Sensing for Real-time Intraoperative Surgical Margin Assessment

for
Prostate Cancer
Location: Lebanon NH
Sponsor: Ryan J. Halter

Sex: Male

Age: 18+

Code: NCT06039085

Recruiting

Lymfit to Improve the Fitness and Quality of Life in Lymphoma Survivors

for
Lymphoma, Cancer Survivors
Location: Montreal
Sponsor: McGill University

Sex: All

Age: 18 - 39

Code: NCT05257785

Recruiting

Radiation Prior to TKI to Delay Progression in Advanced Driver-Mutated Non-small Cell Lung Cancers (RadiaNCe Lung X)

for
Non Small Cell Lung Cancer
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18+

Code: NCT06305715

Phase2, Recruiting

A Multi-Modality Surveillance Program for Women at High Risk for Breast Cancer

for
Breast Cancer
Location: Chicago IL, La Jolla CA, Sacramento CA
Sponsor: University of Chicago

Sex: Female

Age: 25+

Code: NCT03729115

Recruiting

A Novel Multiplex ELISA Assay for Surveilling Patients With History of Bladder Cancer

for
Bladder Cancer
Location: Los Angeles CA
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18+

Code: NCT03193515

Recruiting

FDG-PET and Circulating HPV in Patients With Cervical Cancer Treated With Definitive Chemoradiation (II)

for
Cervical Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: Female

Age: 18+

Code: NCT03853915

Recruiting

A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)

for
Solid Tumors
Location: New Haven CT, Hackensack NJ, Los Angeles CA
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT05471856

Phase1, Recruiting

Food for Thought - A Nutrition Intervention for Women Undergoing Active Treatment for Triple Negative Breast Cancer

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: New Haven CT, Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: Female

Age: 40 - 65

Code: NCT06582615

Recruiting

Serial Imaging of the Novel Radiotracer [^18F] FLuorthanatrace ([^18F] FTT) by PET/CTF

for
Breast Carcinoma, Fallopian Tube Carcinoma, Ovarian Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 18+

Code: NCT03604315

Phase1, Recruiting

A Study of VET3-TGI in Patients With Solid Tumors

for
Solid Tumor, Adult, Microsatellite Stable Colorectal Cancer,
Location: Miami FL, Pittsburgh PA, Indianapolis IN, Houston TX,
Sponsor: KaliVir Immunotherapeutics

Sex: All

Age: 18+

Code: NCT06444815

Phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer