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Oncology Clinical Trials

Browse 9,028 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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PROSPECT - Profiling of Resistance Patterns & Oncogenic Signaling Pathways in Evaluation of Cancers of the Thorax and Therapeutic Target Identification

for
Lung Cancer, Cancer of Thorax
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05049837

Recruiting

Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body

for
Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion,
Location: South Portland ME, Boston MA, New Haven CT, New York NY,
Sponsor: Bayer

Sex: All

Age: 0+

Code: NCT04142437

Recruiting

Post-prostatectomy Radiation Therapy--Moderate Versus Ultra-hypofractionated (Also Known as Stereotactic Body Radiation Therapy [SBRT])

for
Prostate Cancer
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: Male

Age: 18+

Code: NCT05038332

Phase2, Recruiting

A Study of AND019 in Women With ER Positive HER2 Negative Advanced or Metastatic Breast Cancer

for
Advanced or Metastatic Breast Cancer
Location: Nashville TN
Sponsor: Kind Pharmaceuticals LLC

Sex: Female

Age: 18+

Code: NCT05187832

Phase1, Recruiting

Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Breast Cancer

for
Early Stage Breast Cancer
Location: Hartford CT, New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 21 - 70+

Code: NCT04458532

Recruiting

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The STOP-MED CTRCD Trial

for
Heart Failure, Cardiotoxicity, Cardiac Toxicity,
Location: Boston MA, Ottawa, Toronto, Winnipeg, Edmonton
Sponsor: Dinesh Thavendiranathan

Sex: All

Age: 18+

Code: NCT06183437

Recruiting

64Cu-GRIP B in Patients With Advanced Malignancies

for
Prostate Cancer, Renal Cancer, Urethral Cancer,
Location: San Francisco CA
Sponsor: Rahul Aggarwal

Sex: All

Age: 18+

Code: NCT05888532

Phase1, Phase2, Recruiting

Evaluation of a Telehealth Oncofertility Care Intervention in Adolescent and Young Adult Cancer Patients

for
Cancer, Fertility Preservation
Location: San Diego CA, La Jolla CA, Duarte CA
Sponsor: University of California, San Diego

Sex: All

Age: 0 - 50

Code: NCT05443737

Phase3, Recruiting

The C-MERIT Screening Cohort: Contrast-enhanced Mammography for Breast Cancer Screening and Risk Assessment in Women With Dense Breasts

for
Breast Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: Female

Age: 30 - 70+

Code: NCT05667532

Recruiting

A Mobile Health Intervention Among Hispanics

for
Cancer of Skin
Location: New Brunswick NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18 - 70+

Code: NCT05389332

Recruiting

Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance

for
Non-muscle-invasive Bladder Cancer
Location: West Roxbury MA, Lebanon NH, West Haven CT,
Sponsor: White River Junction Veterans Affairs Medical Center

Sex: All

Age: 18+

Code: NCT05796375

Phase2, Recruiting

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

for
Hematologic Neoplasms
Location: Philadelphia PA, Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12 - 70+

Code: NCT04959175

Phase1, Phase2, Recruiting

Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)

for
Ovarian Cancer
Location: New York NY, Newport News VA, Baltimore MD, York PA,
Sponsor: NX Development Corp

Sex: Female

Age: 18+

Code: NCT05804370

Phase3, Recruiting

A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

for
HER2-positive Gastric Cancer,
Location: Chicoutimi, New York NY, Summit NJ, Montreal,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06764875

Phase3, Recruiting

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

for
Advanced Systemic Mastocytosis (AdvSM),
Location: Boston MA, Charleston SC, Toronto, Atlanta GA,
Sponsor: Cogent Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT04996875

Phase2, Recruiting

Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC

for
Head and Neck Squamous Cell Carcinoma, Head and Neck Cancer,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT05726370

Phase2, Recruiting

Erector Spinae Versus Intercostal Nerve Blocks With Liposomal Bupivacaine for Analgesia in Thoracic Surgery

for
Lung Cancers
Location: Washington D.C. DC
Sponsor: George Washington University

Sex: All

Age: 18 - 70+

Code: NCT06810375

Phase3, Recruiting

Confocal Laser Endomicroscopy VERification

for
Lung Cancer, Lung Neoplasm Malignant,
Location: New York NY
Sponsor: Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)

Sex: All

Age: 18+

Code: NCT06079970

Recruiting

A Study Comparing Perioperative Stress Reduction vs. Standard of Care in Ovarian Cancer (PRESERVE)

for
Ovarian Cancer, Ovarian Carcinoma, Stage II Ovary Cancer,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female

Age: 18+

Code: NCT05429970

Recruiting

Secondary Prevention of VTE in Patients With Cancer and Catheter-Related Upper Extremity Deep Vein Thrombosis

for
Venous Thromboembolism, Cancer,
Location: Ottawa
Sponsor: Ottawa Hospital Research Institute

Sex: All

Age: 18+

Code: NCT06603870

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer