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Oncology Clinical Trials

Browse 8,863 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Tesetaxel in Chemotherapy-naive Patients With Progressive, Castration-resistant Prostate Cancer

for
Prostate Cancer
Location: New York NY, New Brunswick NJ, Ann Arbor MI, Madison WI
Sponsor: Genta Incorporated

Sex: Male

Age: 18+

Code: NCT01296243

Phase2, Recruiting

18F-Fluciclovine PET-MRI in High-grade Glioma

for
Glioma, High Grade Glioma, Glioma, Malignant,
Location: Philadelphia PA
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 1 - 21

Code: NCT05553041

Early_phase1, Recruiting

A Survey of Physician and Molecular Tumor Board Perspectives on the Clinical Utility and Usability of Cellworks Singula™ and Ventura™ Reports in Facilitating Patient Treatment Decisions for Pan-Cancer Patients

for
Pan-cancer
Location: Sioux Falls SD
Sponsor: Avera McKennan Hospital & University Health Center

Sex: All

Age: 0+

Code: NCT05308784

Recruiting

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

for
Primary Biliary Cholangitis
Location: Boston MA, Quebec, New York NY, Manhasset NY, Montreal,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT06051617

Phase3, Recruiting

A Study of ADRX-0405 in Subjects With Select Advanced Solid Tumors

for
Solid Tumors
Location: Fairfax VA, Grand Rapids MI, Minneapolis MN, Houston TX,
Sponsor: Adcentrx Therapeutics

Sex: All

Age: 18+

Code: NCT06710379

Phase1, Recruiting

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Intrathecal Chemoprophylaxis to Prevent Neurotoxicity Associated With Blinatumomab Therapy for Acute Lymphoblastic Leukemia

for
Acute Lymphoblastic Leukemia
Location: Atlanta GA
Sponsor: Northside Hospital, Inc.

Sex: All

Age: 18+

Code: NCT05519579

Phase2, Recruiting

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

for
Head and Neck Squamous Cell Carcinoma
Location: Boston MA, New York NY, Philadelphia PA, Baltimore MD,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT06163534

Recruiting

Barrett's Esophagitis in Anorexia Nervosa Binge/Purge Subtype

for
Barrett Esophagus, Anorexia Nervosa, Binge Eating/Purging Type,
Location: Denver CO
Sponsor: Denver Health and Hospital Authority

Sex: All

Age: 18 - 65

Code: NCT06532734

Recruiting

Ultrasound Spectroscopy as Early Indicators of Radiation Treatment Response in Prostate, Rectum and Head & Neck Cancers

for
Prostate Cancer, Head and Neck Cancer, Rectal Cancer
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 0+

Code: NCT03908684

Recruiting

Questionnaire Study for Gynecological Cancer Survivors

for
Endometrial Neoplasms, Ovarian Neoplasms,
Location: Washington DC
Sponsor: U.S. Army Medical Research and Development Command

Sex: Female

Age: 20 - 70+

Code: NCT00391664

Recruiting

BostonGene and Exigent Genomic INsight Study

for
Breast Cancer, Non-small Cell Lung Cancer, Melanoma, Sarcoma
Location: Fort Wayne IN, Rogers AR, Houston TX, Tulsa OK,
Sponsor: BostonGene

Sex: All

Age: 18+

Code: NCT06272864

Recruiting

Pembrolizumab and Mogamulizumab in Advanced-stage, Relapsed/Refractory Cutaneous T-cell Lymphomas

for
Cutaneous T Cell Lymphoma, Fungoides Mycosis Sezary Syndrome
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: All

Age: 18+

Code: NCT05956041

Phase2, Recruiting

Patient-Centered Surgical Prehabilitation

for
Bladder Cancer, Cystectomy
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18 - 70+

Code: NCT05715684

Recruiting

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

for
DLBCL, Diffuse Large B-Cell Lymphoma
Location: Valhalla NY, Horsham PA, Boca Raton FL, Hialeah FL,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT05139017

Phase2, Phase3, Recruiting

Syphilis and HIV Point of Care Testing (POCT) in Saskatchewan

for
Syphilis, HIV Infections
Location: Regina
Sponsor: Wellness Wheel Medical Clinic

Sex: All

Age: 16+

Code: NCT05863117

Recruiting

Radiation Therapy With RapidPlan Knowledge-based Planning vs Human-Driven Planning for Treatment of Prostate Cancer

for
Prostate Carcinoma
Location: Scottsdale AZ
Sponsor: Mayo Clinic

Sex: Male

Age: 18+

Code: NCT06625034

Phase3, Recruiting

A Study of Botensilimab and Balstilimab for Rectal Adenocarcinoma

for
Microsatellite Stable Rectal Carcinoma,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06843434

Phase2, Recruiting

2 Ablative RadioTherapy Treatments for Prostate Cancer

for
Prostate Cancer
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: Male

Age: 0+

Code: NCT04654338

Phase2, Phase3, Recruiting

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

for
Acute Leukemia, Acute Lymphoblastic Leukemia,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 0+

Code: NCT04195633

Phase2, Recruiting

Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL

for
Relapsed or Refractory CD19+ B-cell Lymphoma,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05963217

Phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer