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Oncology Clinical Trials

Browse 8,122 oncology clinical trials enrolling across the United States and Canada. 218 people applied to oncology studies last month. Search by city or state to find one near you.

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1

Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc

for
Prostate Cancer
Location: Ann Arbor MI, Indianapolis IN, Hines IL,
Sponsor: VA Office of Research and Development

Sex: Male

Age: 18+

Code: NCT06084338

Phase 2, Recruiting

A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ

for
Breast Ductal Carcinoma In Situ
Location: Jacksonville FL, Rochester MN
Sponsor: Mayo Clinic

Sex: Female

Age: 18+

Code: NCT04144023

Phase 1, Recruiting

Development of Liquid Biopsy Technologies for Noninvasive Cancer Diagnostics in Patients With Suspicious Thyroid Nodules or Thyroid Cancer

for
Thyroid Gland Carcinoma, Thyroid Gland Nodule
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT04742608

Recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.

for
High-grade Serous Ovarian Carcinoma (HGSOC),
Location: Hackensack NJ, Montreal, Toronto, Vancouver,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06476808

Phase 1, Recruiting

Light vs. Moderate Intensity Exercise in Individuals With Myasthenia Gravis

for
Myasthenia Gravis
Location: Saint Paul MN
Sponsor: HealthPartners Institute

Sex: All

Age: 18 - 70+

Code: NCT06491238

Recruiting

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Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy

for
Colorectal Surgery, Colorectal Cancer, Rectal/Anal,
Location: Hershey PA, Buffalo NY, Houston TX
Sponsor: JSR Medical Co., Ltd.

Sex: All

Age: 19 - 70+

Code: NCT05826743

Recruiting

I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm Patients

for
Myeloproliferative Disorders, Leukemia
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05842603

Recruiting

Prophylactic EUS-guided Gastroenterostomy in Advanced Periampullary Cancers

for
Cancer Gi
Location: Montreal
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All

Age: 18 - 70+

Code: NCT05994521

Recruiting

A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)

for
Acute Leukemia, Lymphoblastic Leukemia, Lymphoblastic Lymphoma
Location: Rochester NY, Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT06207123

Phase 1, Phase 2, Recruiting

Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity

for
Non-Small Cell Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT01639508

Phase 2, Recruiting

The Effects of Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients

for
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma,
Location: Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 70+

Code: NCT05876923

Recruiting

Durvalumab in Different Combinations With Pralatrexate, Romidepsin and Oral 5-Azacitidine for Lymphoma

for
Lymphoma, T-Cell
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: All

Age: 18+

Code: NCT03161223

Phase 1, Phase 2, Recruiting

Economic Analysis of Early vs Delayed Therapy in Newly Diagnosed Asymptomatic High-Risk Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma:

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Saint John, Montreal, Winnipeg, Vancouver
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT05371808

Recruiting

Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders

for
Kidney Cancer, Urologic Malignant Disorders,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 2+

Code: NCT00001238

Recruiting

Smoldering Myeloma High-Risk Patient Observation and Longitudinal Insight Trial

for
Smoldering Multiple Myeloma
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT06212323

Recruiting

A Study of ARV-393 in Relapsed/Refractory Non-Hodgkin Lymphoma.

for
Relapsed/Refractory (R/R) Mature B Cell Non Hodgkin Lymphoma (NHL),
Location: New Haven CT, New York NY, New Brunswick NJ, Montreal,
Sponsor: Arvinas Inc.

Sex: All

Age: 18+

Code: NCT06393738

Phase 1, Recruiting

A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma

for
Follicular Lymphoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06043323

Phase 2, Recruiting

In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma

for
Bone Sarcoma, Soft Tissue Sarcoma, Pulmonary Metastases
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 0 - 64

Code: NCT02811523

Phase 1, Recruiting

Exercise and Nutritional Prehabilitation for Head and Neck Cancer Patients

for
Head Cancer, Neck Cancer, Sarcopenia, Head and Neck Cancer
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06722508

Recruiting

Histiocytic Disorder Follow-up Study

for
Histiocytosis, Langerhans Cell Histiocytosis,
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 0 - 70+

Code: NCT05915208

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer