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Opioid Use Disorder Clinical Trials

Browse 196 Opioid Use Disorder clinical trials enrolling across the United States and Canada. 87 people applied to Opioid Use Disorder studies last month. Search by city or state to find one near you.

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1

NavSTAR Implementation Effectiveness Trial Across a Health System

for
Opioid Use Disorder
Location: Philadelphia PA
Sponsor: Friends Research Institute, Inc.

Sex: All

Age: 18+

Code: NCT07262190

Recruiting

Psilocybin on Brain Mechanisms of Motivation in OUD

for
Opioid Use Disorder
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18 - 60

Code: NCT06810310

Phase2, Recruiting

Systems Analysis and Improvement to Optimize Opioid Use Disorder Care Quality and Continuity for Patients Exiting Jail

for
Opioid Use Disorder, Opioid Use Disorders
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18 - 70+

Code: NCT06593353

Recruiting

Mapping Ibogaine Neural Dynamics in Opioid Use Disorder

for
Opioid Use Disorder (OUD)
Location: Irvine CA
Sponsor: University of California, Irvine

Sex: All

Age: 21 - 70

Code: NCT07226570

Recruiting

Ketamine for Opioid Use Disorder

for
Opioid Use Disorder
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18 - 65

Code: NCT06943859

Phase2, Recruiting

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Personalized Addiction Treatment enHancement

for
Opioid Use Disorder, mHealth, Peer Support
Location: Providence RI
Sponsor: Rhode Island Hospital

Sex: All

Age: 22+

Code: NCT07778394

Recruiting

Cerebral Physiology of NOWS

for
Neonatal Opioid Withdrawal, Neonatal Opioid Withdrawal Syndrome,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 0

Code: NCT07610746

Recruiting

MethaLoad Dose-Finding Study

for
Opioid Use Disorder (OUD)
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT06877858

Phase1, Recruiting

The Effect of Light Intervention on Recovery in Individuals With Opioid Use Disorder (OUD)

for
Opioid Use Disorder, Sleep, Circadian Rhythms, fMRI Research
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18 - 60

Code: NCT06832007

Recruiting

Technology-Enhanced Therapy vs. Medication Monitoring for Buprenorphine Retention in Pregnant Persons

for
Opioid Use Disorder, Pregnancy
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: Female

Age: 18 - 45

Code: NCT06999811

Recruiting

Emergency Medicine Peer Outreach Worker Engagement for Recovery

for
Substance Use Disorders, Overdose, Opioid Use Disorder,
Location: Providence RI
Sponsor: University of California, Los Angeles

Sex: All

Age: 18+

Code: NCT06320015

Recruiting

Wellcome Leap Psilocybin for OUD

for
Opioid Use Disorder
Location: Philadelphia PA
Sponsor: Anna Rose Childress, Ph.D.

Sex: All

Age: 18 - 60

Code: NCT06786325

Phase2, Recruiting

Mindfulness Texting for Medication Adherence and Chronic Pain Management

for
Opioid Use Disorder (OUD), Chronic Pain
Location: Albuquerque NM
Sponsor: University of New Mexico

Sex: All

Age: 18+

Code: NCT07711795

Recruiting

Identifying Biomarkers Related to Opioid Use and Pain Response Following Traumatic Injury and Surgery

for
Opioid Use Disorder, Opioid Consumption, Persistent Opioid Use,
Location: La Jolla CA
Sponsor: University of California, San Diego

Sex: All

Age: 18+

Code: NCT07693270

Recruiting

Towards Testing the Effectiveness of Recovery Community Centers (RCCs)

for
Opioid Use Disorder
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07010978

Recruiting

Measuring Acute Drug Demand in Humans

for
Opioid Use Disorder, Opioid Dependence
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18 - 65

Code: NCT05829655

Early_phase1, Recruiting

Coordinating Outpatient bupreNorphiNe for Emergency Care and Continuing Treatment

for
Opioid Use Disorder
Location: Placerville CA, Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 14+

Code: NCT07024498

Recruiting

Sparrow Link Neuromodulation Device for Opioid Withdrawal Management in Hospitalized Adults With Opioid Use Disorder

for
Opioid Withdrawal, Opioid Use Disorder (OUD)
Location: Pittsburgh PA
Sponsor: Payel Roy

Sex: All

Age: 18+

Code: NCT07079826

Recruiting

Impact of Federal and State Medications for Opioid Use Disorder (MOUD) Policy Changes During the Pandemic

for
Substance Use Disorders, Alcohol Use Disorder,
Location: Boston MA
Sponsor: Boston University

Sex: All

Age: 18+

Code: NCT07232641

Recruiting

Right Tools, Right Time, Right Place: Telehealth for Opioid Use Disorder in Vulnerable Settings

for
Opioid Use Disorder
Location: Portland OR
Sponsor: Boulder Care

Sex: All

Age: 18+

Code: NCT07169409

Phase1, Recruiting

What are Opioid Use Disorder clinical trials?

Opioid use disorder is now understood much like other chronic health conditions: ongoing management and support tend to work far better than a single fixed intervention, similar to how diabetes or high blood pressure are managed over time rather than resolved once. Opioid Use Disorder clinical trials are research studies that explore different approaches to supporting recovery, reducing overdose risk, and helping people manage cravings and withdrawal. Researchers use these studies to better understand what actually helps people build long-term recovery, and how different types of support, including counseling and medications for opioid use disorder, affect outcomes over time.

The importance of clinical trials in Opioid Use Disorder research

Opioid clinical trials are an important part of how opioid use disorder is understood and addressed at a national level. They help researchers learn more about recovery patterns, identify what kind of support works best for different people, and offer structured, closely monitored pathways for those seeking help. This kind of research also helps shape recovery programs and public health efforts nationwide.

Types of Opioid Use Disorder clinical trials

Who can participate in Opioid Use Disorder clinical trials?

Does information stay confidential when participating in an Opioid Use Disorder clinical trial?

How to enroll in a clinical trial for Opioid Use Disorder