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Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

Life at 100.4: An Immersive Social Virtual Reality (VR) Education Tool for Adolescent and Young Adult Cancer Patients and Caregivers

for
Cancer, Adolescent Cancer, Young Adult Cancer
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 13 - 39

Code: NCT07224204

Recruiting
Active & Responsive

A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.

for
Locally Advanced Pancreatic Adenocarcinoma,
Location: Detroit MI, Houston TX, Santa Fe NM, Irvine CA,
Sponsor: Xerient Pharma

Sex: All

Age: 18+

Code: NCT07157033

Phase1, Phase2, Recruiting
Active & Responsive

Virtual Mindful After Cancer (MAC) Intervention to Promote Sexual Health for Breast and Gynecologic Cancer Survivors

for
Gynecologic Cancers, Breast Cancer
Location: Philadelphia PA, Corvallis OR
Sponsor: Oregon State University

Sex: Female

Age: 18+

Code: NCT07055854

Phase1, Recruiting
Active & Responsive

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

for
Advanced Solid Tumors, Metastatic Solid Tumors,
Location: Norwich CT, Fairfax VA, Nashville TN, Saint Paul MN,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07397338

Phase1, Phase2, Recruiting
Active & Responsive

Evaluation of RAS Inhibitor Treatment in Participants With Advanced or Metastatic Solid Tumors Harboring RAS Mutations

for
Solid Tumors (Phase 1), RAS Mutation
Location: Orlando FL, Houston TX
Sponsor: Adlai Nortye Biopharma Co., Ltd.

Sex: All

Age: 18+

Code: NCT07252479

Phase1, Recruiting

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Active & Responsive

Using Plasma Human Papillomavirus (HPV)-Related Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA) to Follow Response of Cervical Cancer to Surgery, Radiation, and Chemotherapy

for
Cervical Cancer, Human Papilloma Virus (HPV)
Location: Gainesville FL
Sponsor: University of Florida

Sex: Female

Age: 18 - 70+

Code: NCT07214584

Recruiting
Active & Responsive

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

for
Head and Neck Cancer, Squamous Cell Carcinoma,
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT07209189

Phase2, Recruiting
Active & Responsive

A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

for
Chronic Lymphocytic Leukemia, B-cell Malignancies
Location: Florham Park NJ, Miami Beach FL, Pittsburgh PA,
Sponsor: Curis, Inc.

Sex: All

Age: 18+

Code: NCT07271667

Phase2, Recruiting
Active & Responsive

iCANSleep: Smartphone App-Based Insomnia Treatment for Cancer Survivors

for
Insomnia, Cancer
Location: St. John's
Sponsor: Memorial University of Newfoundland

Sex: All

Age: 18+

Code: NCT07101302

Recruiting
Active & Responsive

FIH Study to Evaluate Safety, Tolerability, PK, PD & Preliminary Efficacy of AT03-65 With Advanced Solid Tumors

for
Solid Tumor
Location: Portland OR
Sponsor: Axcynsis Therapeutics Pte Ltd

Sex: All

Age: 18+

Code: NCT06809114

Phase1, Recruiting
Active & Responsive

Intrathecal Cytarabine, Methotrexate, and Hydrocortisone for the Prevention of High-Grade Chimeric Antigen Receptor T-Cell-Associated Neurotoxicity Syndrome

for
Hematopoietic and Lymphatic System Neoplasm
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT06895473

Phase2, Recruiting
Active & Responsive

IKS014 in Advanced Solid Tumors That Express HER2

for
Breast Cancer, Gastric Cancer, Gastroesophageal-junction Cancer
Location: Boston MA, Nashville TN, Fort Worth TX,
Sponsor: Iksuda Therapeutics Ltd.

Sex: All

Age: 18+

Code: NCT05872295

Phase1, Recruiting
Active & Responsive

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

for
Castration-Resistant Prostate Cancer (CRPC), Colorectal Cancer,
Location: Dothan AL, Grand Rapids MI, Omaha NE
Sponsor: Radiopharm Theranostics, Ltd

Sex: All

Age: 18+

Code: NCT07189871

Phase1, Phase2, Recruiting
Active & Responsive

Cognitive Impact of Neoadjuvant Chemotherapy for Gynecologic Cancers

for
Ovarian Cancer, Cognitive Change
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: Female

Age: 18+

Code: NCT07125209

Recruiting
Active & Responsive

Testing the Feasibility of a Virtual Application to Support Breast and Colorectal Cancer Survivors

for
Breast Cancer Survivor, Colorectal Cancer Survivors
Location: Halifax
Sponsor: Nova Scotia Health Authority

Sex: All

Age: 18+

Code: NCT07312786

Recruiting
Active & Responsive

A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec

for
Prostate Cancer Patients Treated by Radiotherapy,
Location: Saddle Brook NJ, Towson MD, Myrtle Beach SC,
Sponsor: Candel Therapeutics, Inc.

Sex: Male

Age: 18+

Code: NCT07332000

Phase2, Recruiting
Active & Responsive

A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)

for
Malignant Neoplasm
Location: Quebec, New Brunswick NJ, Montreal, Fairfax VA, Toronto,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07247110

Phase1, Recruiting
Active & Responsive

Study of PAT in Patients With Solid Tumor Cancers

for
Metastasis, Solid Tumor
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT05338658

Phase1, Recruiting
Active & Responsive

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

for
Colorectal Cancer, Colorectal Cancer (CRC),
Location: Fairfax VA, Jacksonville FL, Atlanta GA,
Sponsor: Cartography Biosciences

Sex: All

Age: 18+

Code: NCT07321106

Phase1, Recruiting
Active & Responsive

Evaluation of Early Identification of Cognitive Side Effects of Immunotherapy

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT06414278

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer