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Oncology Clinical Trials

Browse 8,977 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

Bladder EpiCheck Product Development Study

for
Suspicion of Bladder Cancer, NMIBC Surveillance
Location: Towson MD, San Diego CA
Sponsor: Nucleix Ltd.

Sex: All

Age: 22+

Code: NCT07514143

Recruiting
Active & Responsive

A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma

for
Multiple Myeloma in Relapse, Myeloma Multiple,
Location: Boston MA, Hackensack NJ, Tampa FL, Atlanta GA,
Sponsor: Kelonia Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07075185

Phase1, Recruiting
Active & Responsive

A Study of TAK-505 in Adults With Solid Tumors

for
Malignant Solid Tumors
Location: Fairfax VA, Tampa FL, Nashville TN, Minneapolis MN,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT07436728

Phase1, Phase2, Recruiting
Active & Responsive

Optimize Neoadjuvant Therapy in HER2-Positive Early-Stage Breast Cancer

for
HER2-positive Early-stage Breast Cancer
Location: Long Branch NJ, Toms River NJ, Elizabeth NJ, Newark NJ,
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18 - 70+

Code: NCT07402473

Phase2, Recruiting
Active & Responsive

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

for
Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive,
Location: Boston MA, Atlanta GA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT07020533

Phase1, Recruiting

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Active & Responsive

Effects of Latin Dancing on Sleep Quality in Hispanic Cancer Survivors

for
Cancer Survivorship, Sleep Disturbances
Location: New Brunswick NJ
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18+

Code: NCT06844981

Recruiting
Active & Responsive

A Pancreatic Cancer Screening Study in Individuals With New-Onset or Deteriorating Diabetes Mellitus

for
Pancreatic Cancer, Pancreatic Neoplasms, Diabetes Mellitus
Location: Norwalk CT
Sponsor: Nuvance Health

Sex: All

Age: 50+

Code: NCT03937453

Recruiting
Active & Responsive

Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer

for
Metastatic Colorectal Adenocarcinoma,
Location: Baltimore MD, Washington D.C. DC, Atlanta GA, Aurora CO
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07147231

Phase1, Phase2, Recruiting
Active & Responsive

mHealth Intervention for Pain Self Management

for
Pain, Pain Management, Symptom Monitoring, Symptom Management,
Location: Richmond VA
Sponsor: Virginia Commonwealth University

Sex: All

Age: 18+

Code: NCT07332377

Recruiting
Active & Responsive

A Study of ELA026 in Participants With Relapsed/Refractory (R/R) T/NK Cell Malignancies (TCMs)

for
T Cell Malignancies
Location: New Haven CT, New York NY, Cleveland OH, Atlanta GA,
Sponsor: Electra Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT07465835

Phase1, Recruiting
Active & Responsive

A Cancer Vaccine (STEMVAC) in Combination With Chemotherapy for the Treatment of PD-L1 Negative Metastatic Triple-Negative Breast Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT07078604

Phase2, Recruiting
Active & Responsive

PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease

for
Breast Cancer, Residual Disease,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07069595

Phase2, Recruiting
Active & Responsive

Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

for
Endometrial Cancer, Ovarian Cancer, Ovarian Cancer Metastatic,
Location: Hackensack NJ, Fairfax VA, Buffalo NY, Cleveland OH,
Sponsor: Whitehawk Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07444814

Phase1, Recruiting
Active & Responsive

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

for
AML (Acute Myeloid Leukemia), Glioma, Cholangiocarcinoma,
Location: New York NY, Orange CA
Sponsor: Rigel Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07486713

Recruiting
Active & Responsive

KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)

for
Bladder Cancer
Location: Cleveland OH, Chicago IL, Salt Lake City UT,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07232602

Phase1, Phase2, Recruiting
Active & Responsive

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for
Glioblastoma (GBM), Newly Diagnosed Glioblastoma, GBM,
Location: Boston MA, New Haven CT, Lake Success NY, The Bronx NY,
Sponsor: Black Diamond Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07326566

Phase2, Recruiting
Active & Responsive

Ambient Sensing Room to Detect Early Signs of Adverse Events in Hospitalized Patients With Cancer

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07477886

Recruiting
Active & Responsive

Clinical Validation of Early Detection Blood Test for Universal Large-scale Breast Cancer Screening

for
Breast Cancer, Liquid Biopsy, Early Detection
Location: Phoenix AZ
Sponsor: Syantra Inc.

Sex: Female

Age: 30 - 70+

Code: NCT07219277

Recruiting
Active & Responsive

Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

for
Rectal Adenocarcinoma, Rectal Cancer
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT07292298

Phase2, Recruiting
Active & Responsive

Efficacy and Safety Evaluation of VS-101 in Combination With Chemoradiotherapy in Patients With Head and Neck Cancer

for
Head and Neck Cancer Squamous Cell Carcinoma
Location: New Haven CT, Manhattan NY
Sponsor: VSPharmTech Co.,Ltd.

Sex: All

Age: 18+

Code: NCT06959082

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer