Background illustration for clinical trials search

Oncology Clinical Trials

Browse 9,238 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

Filter
1
Active & Responsive

A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Boston MA, New Haven CT, New York NY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07111520

Phase1, Phase2, Recruiting
Active & Responsive

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

for
Prostate Cancer Castration-resistant Prostate Cancer,
Location: East Brunswick NJ, Fairfax VA, Grand Rapids MI,
Sponsor: MBrace Therapeutics

Sex: All

Age: 18+

Code: NCT07145255

Phase1, Phase2, Recruiting
Active & Responsive

[18F]FTT Positron Emission Tomography for the Measurement of PARP Tumor Expression in Patients With Metastatic Breast Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT06502691

Phase1, Phase2, Recruiting
Active & Responsive

Preventing Dato-DXd Associated Stomatitis With Dexamethasone Mouthwash, TROPION-DM

for
Breast Neoplasms, Lung Neoplasms
Location: Providence RI
Sponsor: Brown University

Sex: All

Age: 18+

Code: NCT06974604

Phase2, Recruiting
Active & Responsive

Lenvatinib 24 mg/Day Versus 10 mg/Day to Treat Symptomatic or Progressive Radioactive Iodine Resistant (RAIR) Differentiated Thyroid Cancer (DTC)

for
Thyroid Cancer, Cancer of the Thyroid
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07092514

Phase2, Recruiting

Interested in new trials?

Get alerts for new trials in your area by subscribing now

Subscriber Image
Active & Responsive

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

for
Solid Tumors
Location: Baltimore MD
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07492680

Phase2, Recruiting
Active & Responsive

Safety and Efficacy of Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA) in the Treatment of Pancreatic Lesions

for
Pancreatic Cancer
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 18+

Code: NCT07737171

Recruiting
Active & Responsive

A Vaccine (STEMVAC) With Standard Endocrine-Based Therapy or Chemotherapy for the Treatment of Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT07112053

Phase2, Recruiting
Active & Responsive

A Study of Tolododekin Alfa (ANK-101) in Combination With an Anti-PD-1/PD-L1 Antibody in Participants With Advanced Non-Small Cell Lung Cancer

for
Non Small Cell Lung Cancer
Location: New York NY, Philadelphia PA, Coral Gables FL,
Sponsor: Ankyra Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT07027514

Phase1, Recruiting
Active & Responsive

Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast Cancer Study

for
Breast Cancer, Breast Neoplasms
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: Female

Age: 20 - 70+

Code: NCT07214610

Recruiting
Active & Responsive

Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT

for
Ovarian Cancer, Cognitive Impairment
Location: Orange CA
Sponsor: University of California, Irvine

Sex: Female

Age: 18+

Code: NCT04520139

Phase1, Phase2, Recruiting
Active & Responsive

DBC-664 in Adult Patients With Solid Tumors

for
Malignant Germ Cell Tumor, Lung Adenocarcinoma,
Location: Lake Success NY, East Brunswick NJ, Grand Rapids MI,
Sponsor: Duboce Biopharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07705035

Phase1, Recruiting
Active & Responsive

PDT For Induction Therapy For Head And Neck Cancer

for
Squamous Cell Carcinoma,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07214987

Phase2, Recruiting
Active & Responsive

Capturing Food Intake in Patients Undergoing Radiation Therapy for Cancer

for
Cancer, Radiation Therapy, Dietary Intake
Location: Minneapolis MN
Sponsor: University of Minnesota

Sex: All

Age: 18+

Code: NCT07682714

Recruiting
Active & Responsive

A Study of Lung Cancer Risk

for
Lung Cancer
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 40 - 70+

Code: NCT07701733

Recruiting
Active & Responsive

LRG GIST Patient Registry

for
GIST, GIST - Gastrointestinal Stromal Tumor,
Location: Wayne NJ
Sponsor: The Life Raft Group

Sex: All

Age: 0+

Code: NCT07697248

Recruiting
Active & Responsive

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

for
Extensive Stage Lung Small Cell Carcinoma,
Location: North Haven CT, New Haven CT, Trumbull CT, New York NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06287775

Phase1, Phase2, Recruiting
Active & Responsive

Immunotherapy (Toripalimab) for Reducing Recurrence Risk After Surgery for Mismatch Repair Deficient Stage IIB, IIC, or III Colon Cancer

for
Localized Colon Carcinoma, Stage IIB Colon Cancer AJCC v8,
Location: Johns Creek GA, Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT07140679

Phase2, Recruiting
Active & Responsive

Fast-Her: Fasting Effects on Breast Cancer Treatment

for
Metastatic Breast Cancer
Location: Minneapolis MN
Sponsor: University of Minnesota

Sex: All

Age: 18+

Code: NCT07624617

Recruiting
Active & Responsive

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

for
Colorectal Cancer
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT07281768

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer