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Oncology Clinical Trials

Browse 8,894 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Key Longitudinal Associations With Risk and Glioblastoma Outcomes

for
Glioblastoma
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06625684

Recruiting

FDG and FDOPA PET Demonstration of Functional Brain Abnormalities

for
Glioblastoma
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: All

Age: 18+

Code: NCT04315584

Early_phase1, Recruiting

Assessment of Endometrial Thickness Among Adolescent and Young Adult Patients on Estrogen Replacement Therapy Using Daily Oral Micronized Progesterone Versus the Etonogestrel Implant.

for
Primary Ovarian Insufficiency, Hypogonadotropic Hypogonadism,
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: Female

Age: 12 - 25

Code: NCT06357442

Recruiting

Vaccine Responses in Patients With B Cell Malignancies

for
Lymphoma
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT05170399

Recruiting

Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination With Pembrolizumab, in Unresectable Melanoma Patients

for
Melanoma Stage III, Melanoma Stage IV
Location: Hartford CT, New York NY
Sponsor: Philogen S.p.A.

Sex: All

Age: 18+

Code: NCT06284590

Phase2, Recruiting

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The Purpose of This Research Study is to See if Combining Gemcitabine, Cisplatin and Durvalumab Chemotherapy Treatments With a Direct Tumor Therapy Yittrium-90 (Y-90) Will Work Better Together to Shrink Tumors and Control Cancer

for
Intrahepatic Cholangiocarcinoma
Location: Fairfax VA
Sponsor: Inova Health Care Services

Sex: All

Age: 18+

Code: NCT05422690

Phase2, Recruiting

Comparing Direct vs Indirect Methods for Cascade Screening

for
Long QT Syndrome, Familial Hypercholesterolemia, Ethics,
Location: Lancaster PA
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT05348564

Recruiting

Peripheral Blood Flow Responses to Electromagnetic Energy

for
Exposure to Man-made Visible Light
Location: Milwaukee WI
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18 - 59

Code: NCT02370199

Recruiting

Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer

for
Breast Carcinoma
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: Female

Age: 21+

Code: NCT04913064

Recruiting

Leflunomide, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma

for
Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
Location: Upland CA, Lancaster CA, Duarte CA, Newport Beach CA,
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT04508790

Phase2, Recruiting

HN-QUEST: A Study of Head and Neck Imaging Biomarkers

for
Head and Neck Squamous Cell Carcinoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05919290

Recruiting

Safety of Combining Irinotecan With 5-FU, Leucovorin/Folinic Acid, Oxaliplatin, and Docetaxel Chemotherapies

for
Pancreatic Adenocarcinoma,
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT04361708

Phase1, Recruiting

Community Health Workers And MHealth to ImProve Viral Suppression Plus (CHAMPS+)

for
HIV/AIDS
Location: Opelika AL, Hobson City AL, New Orleans LA, Jackson MS
Sponsor: Columbia University

Sex: All

Age: 18+

Code: NCT06472206

Recruiting

5-ALA in Recurrent Glioma

for
Glioma
Location: Phoenix AZ
Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All

Age: 18+

Code: NCT02119338

Recruiting

An Extension to Assess the Effect of Expanded Dialysis on Patient Reported Symptoms Using LEVIL

for
End Stage Renal Disease
Location: Halifax, London, Winnipeg
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 18+

Code: NCT06032208

Recruiting

Amiodarone for the Prevention of Atrial Fibrillation After Minimally Invasive Esophagectomy in Patients With Esophageal Cancer

for
Atrial Fibrillation, Esophageal Carcinoma
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT06067438

Phase2, Recruiting

RP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node Metastasis

for
Melanoma
Location: Pittsburgh PA
Sponsor: Yana Najjar

Sex: All

Age: 18+

Code: NCT06216938

Early_phase1, Recruiting

A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

for
Secondary Hyperparathyroidism, Chronic Kidney Disease
Location: Philadelphia PA, Cleveland OH, Kansas City MO,
Sponsor: Amgen

Sex: All

Age: 0 - 18

Code: NCT03633708

Phase3, Recruiting

A Study to Investigate the Safety and Efficacy of SAR446523 Injected Subcutaneously in Adult Participants With Relapsed/Refractory Myeloma

for
Plasma Cell Myeloma Refractory
Location: Sherbrooke, Hackensack NJ, Montreal, Philadelphia PA,
Sponsor: Sanofi

Sex: All

Age: 18+

Code: NCT06630806

Phase1, Recruiting

Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes

for
Gestational Diabetes, Pregnancy, High Risk,
Location: Providence RI, Pittsburgh PA, Indianapolis IN,
Sponsor: Indiana University

Sex: Female

Age: 18 - 45

Code: NCT05124808

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer