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Paid Clinical Trials Irvine

Discover 3,581 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Featured

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

for
Small Cell Lung Cancer
Location: Irvine CA, Duarte CA, Goodyear AZ, Eugene OR,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07365241

Phase3, Recruiting
Featured

Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

for
Multiple Myeloma
Location: Irvine CA, Duarte CA, Cincinnati OH, Atlanta GA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07555938

Phase3, Recruiting
Featured

A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors

for
Advanced Squamous Tumors
Location: Irvine CA, Duarte CA, Irving TX, Chicago IL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07241039

Phase1, Recruiting
Featured

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for
Breast Cancer
Location: Irvine CA, Duarte CA, La Jolla CA, San Diego CA,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07100106

Phase1, Phase2, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for
Breast Cancer
Location: Irvine CA, Los Alamitos CA, Long Beach CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06790693

Phase3, Recruiting

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Featured

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

for
Hepatocellular Cancer, Squamous-Cell Non-Small Cell Lung Cancer
Location: Irvine CA, Orange CA, Duarte CA, Los Angeles CA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06858813

Phase1, Recruiting
Featured

A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A

for
Hemophilia A
Location: Orange CA, Aurora CO, Seattle WA, Iowa City IA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 12+

Code: NCT07416604

Phase3, Recruiting
Featured

A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A

for
Hemophilia A
Location: Orange CA, San Francisco CA, Vallejo CA
Sponsor: Hoffmann-La Roche

Sex: Male

Age: 18+

Code: NCT07226206

Phase1, Phase2, Recruiting
Featured

A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: Orange CA, Los Angeles CA, Sacramento CA, Houston TX,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT04302025

Phase2, Recruiting
Featured

A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer

for
Breast Cancer
Location: Orange CA, Los Angeles CA, Vancouver, Germantown TN,
Sponsor: Hoffmann-La Roche

Sex: Female

Age: 18+

Code: NCT07054190

Phase2, Recruiting
Featured

A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

for
Depression, Bipolar I Disorder
Location: Orange CA, Anaheim CA, Long Beach CA, Chino CA,
Sponsor: AbbVie

Sex: All

Age: 10 - 17

Code: NCT04777357

Phase3, Recruiting
Featured

A Study to Assess the Safety and Efficacy of AGN-151586 Injections for the Treatment of Moderate to Severe Forehead Lines (FHL) in Adult Participants

for
Forehead Lines
Location: Newport Beach CA, Pflugerville TX, Wilmington NC,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07730554

Phase2, Recruiting
Featured

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Newport Beach CA, Santa Clarita CA, Lancaster CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819891

Phase3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis,
Location: Orange CA, Fountain Valley CA, Long Beach CA,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06318169

Phase3, Recruiting
Featured

A Study Evaluating Adherence, Tolerability, and Patient Reported Outcomes of Giredestrant in Participants With ER+/HER2- Early Breast Cancer Who Are Intolerant to Adjuvant Aromatase Inhibitor Therapy (novERA Breast Cancer)

for
Early Breast Cancer
Location: Fountain Valley CA, Sterling Heights MI
Sponsor: Genentech, Inc.

Sex: Female

Age: 18+

Code: NCT07541079

Phase3, Recruiting
Featured

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

for
Obesity or Overweight, Type 2 Diabetes Mellitus
Location: Lake Forest CA, Long Beach CA, Norco CA, Montclair CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07351058

Phase3, Recruiting
Featured

A Study to Evaluate the Effect of Moderate or Severe Hepatic Impairment on the Pharmacokinetics (PK) of Inavolisib

for
Hepatic Impairment
Location: Lake Forest CA, San Antonio TX, Orlando FL
Sponsor: Genentech, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07144111

Phase1, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for
Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis,
Location: Fountain Valley CA, Los Angeles CA, Pasadena CA,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06419374

Phase3, Recruiting
Featured

Study to Assess the Real-World Effectiveness of Ubrogepant in Adult Participants When Treating During the Prodrome Phase of Migraine Attacks

for
Migraine
Location: Aliso Viejo CA, Grand Island NE, Naperville IL
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07310290

Recruiting
Featured

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

for
Chronic Migraine
Location: Anaheim CA, Long Beach CA, Oceanside CA, Fresno CA,
Sponsor: AbbVie

Sex: All

Age: 12 - 17

Code: NCT06810505

Phase3, Recruiting