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Paid Clinical Trials Irvine

Discover 3,581 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Featured

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

for
Migraine
Location: Anaheim CA, La Palma CA, Oceanside CA, Winnetka CA,
Sponsor: AbbVie

Sex: All

Age: 6 - 17

Code: NCT05125302

Phase3, Recruiting
Featured

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

for
Episodic Migraine
Location: Anaheim CA, Long Beach CA, San Jose CA, Walnut Creek CA,
Sponsor: AbbVie

Sex: All

Age: 6 - 17

Code: NCT05711394

Phase3, Recruiting
Featured

A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer

for
Breast Cancer
Location: Anaheim CA, Palo Alto CA, Pierre SD, Mitchell SD,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07405801

Phase2, Recruiting
FeaturedNew

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

for
Crohn's Disease, Ulcerative Colitis
Location: Anaheim CA, Los Alamitos CA, Rialto CA, Lancaster CA,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07697456

Phase2, Recruiting
Featured

Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

for
Non Small Cell Lung Carcinoma
Location: Fullerton CA, Santa Monica CA, Oxnard CA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06772623

Phase1, Phase2, Recruiting

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Featured

Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL

for
Relapsed or Refractory Aggressive B-Cell Non-Hodgkins Lymphoma
Location: Fullerton CA, Torrance CA, Glendale CA, Los Angeles CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06806033

Phase2, Recruiting
Featured

A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia

for
Schizophrenia
Location: Los Alamitos CA, Glendale CA, Austin TX, Richardson TX,
Sponsor: AbbVie

Sex: All

Age: 18 - 65

Code: NCT07145918

Phase2, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

for
Parkinson's Disease
Location: Fullerton CA, Los Angeles CA, Pasadena CA, La Jolla CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07174310

Phase3, Recruiting
Featured

A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

for
Alzheimers Disease
Location: Long Beach CA, Riverside CA, Sherman Oaks CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07170150

Phase3, Recruiting
Featured

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

for
Lymphoma
Location: Duarte CA, Los Angeles CA, Santa Monica CA, Reno NV,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06084936

Phase3, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity When Intravenous (IV) Pivekimab Sunirine is Given in Combination With Oral Venetoclax and IV or Subcutaneous Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia
Location: Duarte CA, Houston TX, St Louis MO, Atlanta GA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07581002

Phase2, Phase3, Recruiting
Featured

A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer

for
Colorectal Cancer
Location: Duarte CA, Goodyear AZ, Aurora CO, Portland OR,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07525206

Phase3, Recruiting
Featured

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)

for
Neoplasms
Location: Duarte CA, Aurora CO, San Antonio TX, Houston TX,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06884618

Phase1, Recruiting
Featured

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

for
Metastatic Colorectal Cancer
Location: Duarte CA, Santa Monica CA, Seattle WA, Austin TX,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06820463

Phase2, Recruiting
Featured

Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema

for
Diabetic Retinopathy
Location: Torrance CA, Pasadena CA, Encino CA, Poway CA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07592273

Phase2, Phase3, Recruiting
Featured

Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair

for
Ventral Hernia
Location: Riverside CA, Dallas TX, Rochester MN, Evanston IL,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07226791

Phase2, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)

for
Multiple Myeloma
Location: Los Angeles CA, Salt Lake City UT, Portland OR,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06953960

Phase1, Phase2, Recruiting
Featured

To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer

for
Breast Cancer
Location: Los Angeles CA, Kansas City MO, Jacksonville FL,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07368998

Phase2, Recruiting
Featured

A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis

for
Atopic Dermatitis
Location: Los Angeles CA, Alpharetta GA, Troy MI, London,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07223697

Phase2, Recruiting
Featured

A Study to Evaluate the Safety and Effectiveness of Upadacitinib in Pediatric Participants With Alopecia Areata

for
Severe Alopecia Areata
Location: Los Angeles CA, El Paso TX, Meridian ID, San Antonio TX,
Sponsor: AbbVie

Sex: All

Age: 6 - 17

Code: NCT07772492

Phase3, Recruiting