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Paid Clinical Trials Knoxville

Discover 213 paid clinical trials in Knoxville, Tennessee. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Evaluation of Safety and Efficacy of Morpheus8 Applicator for the Treatment of Focal Hyperhidrosis of the Axillae Using Radio Frequency

for
Hyperhidrosis Primary Focal Axilla
Location: Knoxville TN, Dallas TX
Sponsor: InMode MD Ltd.

Sex: All

Age: 18+

Code: NCT05860972

Recruiting

Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

for
Macular Telangiectasia Type 2 (MacTel)
Location: Knoxville TN, Atlanta GA, Cincinnati OH, Cleveland OH,
Sponsor: Neurotech Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06971939

Recruiting

Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab

for
Relapsing Multiple Sclerosis
Location: Knoxville TN, Greenville SC, Atlanta GA, Charlotte NC,
Sponsor: TG Therapeutics, Inc.

Sex: All

Age: 18 - 65

Code: NCT05877963

Phase 3, Recruiting

A Dose-masked Study of Intravitreal Remigromig (EYE103) in Participants With NVAMD or Macular Edema Following BRVO

for
Neovascular Age-Related Macular Degeneration (NVAMD),
Location: Knoxville TN, Asheville NC, Nashville TN, Charleston WV,
Sponsor: EyeBiotech Ltd.

Sex: All

Age: 18+

Code: NCT07205887

Phase 2, Recruiting

A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for
Myelodysplastic Syndromes
Location: Knoxville TN, Nashville TN, Louisville KY,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06499285

Phase 3, Recruiting

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A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

for
DLBCL, Diffuse Large B-Cell Lymphoma
Location: Knoxville TN, Edgewood KY, Niles IL, Grand Rapids MI,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT05139017

Phase 2, Phase 3, Recruiting

A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

for
Prostatic Neoplasms, Castration-Resistant
Location: Knoxville TN, Atlanta GA, Louisville KY, Edgewood KY,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07225946

Phase 3, Recruiting

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

for
Squamous Cell Carcinoma of Head and Neck
Location: Knoxville TN, Lexington KY, Atlanta GA, Nashville TN,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07276399

Phase 3, Recruiting

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

for
Breast Neoplasms, Triple Negative Breast Neoplasms,
Location: Knoxville TN, Greenville SC, Nashville TN, Newnan GA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06966700

Phase 3, Recruiting

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

for
Lymphoma, Large B-Cell, Diffuse
Location: Knoxville TN, Lexington KY, Nashville TN,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06890884

Phase 2, Recruiting

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

for
Non-small Cell Carcinoma, Non-Small Cell Lung Cancer Metastatic,
Location: Knoxville TN, Cleveland TN, Chattanooga TN, Dalton GA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07144280

Phase 3, Recruiting

TR(ACE) Assay Clinical Specimen Study

for
Carcinoma, Non-Small-Cell Lung, Breast Neoplasms
Location: Knoxville TN, Greenville SC, Bloomington IN, Canton OH,
Sponsor: Biological Dynamics

Sex: All

Age: 21+

Code: NCT02934360

Recruiting

Comparison of Epi-ON Corneal Collagen Crosslinking Performed Using an 18-Minute UVA Exposure vs. a 24-Minute UVA Exposure on Eyes With Ectatic Corneal Diseases

for
Keratoconus, Ectasia of Cornea,
Location: Knoxville TN, Asheville NC, Johnson City TN,
Sponsor: Woolfson Eye Institute

Sex: All

Age: 8+

Code: NCT07124910

Phase 3, Recruiting

Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome

for
Down Syndrome (DS), Keratoconus, Pellucid Marginal Degeneration,
Location: Knoxville TN, Asheville NC, Johnson City TN,
Sponsor: Woolfson Eye Institute

Sex: All

Age: 8+

Code: NCT07135167

Phase 3, Recruiting

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

for
Heart Failure, Heart Failure With Reduced Ejection Fraction
Location: Knoxville TN, Atlanta GA, Nashville TN, Tullahoma TN,
Sponsor: Cytokinetics

Sex: All

Age: 18 - 70+

Code: NCT06736574

Phase 3, Recruiting

Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)

for
Pulmonary Embolism
Location: Knoxville TN, Birmingham AL, Chapel Hill NC,
Sponsor: Innova Vascular, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06041594

Recruiting

Alleviant ALLAY-HFrEF Study

for
Heart Failure
Location: Knoxville TN, Asheville NC, Decatur GA, Roanoke VA,
Sponsor: Alleviant Medical, Inc.

Sex: All

Age: 18+

Code: NCT06812533

Recruiting

Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease

for
Peripheral Artery Disease (PAD)
Location: Knoxville TN, Tullahoma TN, Mooresville NC,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07318610

Phase 3, Recruiting

Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

for
Pulmonary Embolism
Location: Knoxville TN, Augusta GA, Cincinnati OH, Kettering OH,
Sponsor: Penumbra Inc.

Sex: All

Age: 18+

Code: NCT04798261

Recruiting

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

for
Peripheral Arterial Disease
Location: Jefferson City TN, Birmingham AL, Newburgh IN,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07223593

Phase 3, Recruiting