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Paid Clinical Trials Knoxville

Discover 213 paid clinical trials in Knoxville, Tennessee. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

for
Obesity, Overweight
Location: Nashville TN, Greenville SC, Dunwoody GA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07321886

Phase 3, Recruiting
Active & Responsive

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

for
Obesity, Overweight
Location: Knoxville TN, Gainesville GA, Greenville SC,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07684235

Phase 3, Recruiting
Active & Responsive

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

for
Atherosclerotic Cardiovascular Disease, Overweight, Obesity
Location: Knoxville TN, Powell TN, Canton GA, Morganton NC,
Sponsor: Amgen

Sex: All

Age: 45 - 70+

Code: NCT07037433

Phase 3, Recruiting
Active & Responsive

A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

for
Influenza, Human
Location: Knoxville TN, Anderson SC, Spartanburg SC, Atlanta GA,
Sponsor: GlaxoSmithKline

Sex: All

Age: 65+

Code: NCT07805707

Phase 3, Recruiting
Active & Responsive

A Study to Learn About a Vaccine Against E Coli in Healthy Adults

for
Healthy Participants
Location: Knoxville TN, Maryville TN, Cincinnati OH,
Sponsor: Pfizer

Sex: All

Age: 18 - 64

Code: NCT07122986

Phase 1, Recruiting

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Active & Responsive

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

for
Diabetes Mellitus, Type 2, Hypertension,
Location: Knoxville TN, Greenville SC, Johns Creek GA, Lenoir NC,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT07064473

Phase 3, Recruiting
Active & Responsive

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

for
Emphysema, Pulmonary, Emphysema or COPD
Location: Knoxville TN, Lexington KY, Pittsburgh PA,
Sponsor: Pulmonx Corporation

Sex: All

Age: 40 - 70+

Code: NCT06035120

Recruiting
Active & Responsive

Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone in Adults With Idiopathic Pulmonary Fibrosis (IPF)

for
Idiopathic Pulmonary Fibrosis (IPF)
Location: Knoxville TN, Franklin TN, Rock Hill SC, Greensboro NC,
Sponsor: PureTech

Sex: All

Age: 40+

Code: NCT07284602

Phase 3, Recruiting
Active & Responsive

Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

for
Generalized Myasthenia Gravis
Location: Knoxville TN, Chattanooga TN, Lexington KY,
Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT04202341

Recruiting
Active & Responsive

Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)

for
Smoking Cessation
Location: Knoxville TN, Nashville TN, Stockbridge GA,
Sponsor: Axsome Therapeutics, Inc.

Sex: All

Age: 18 - 65

Code: NCT07766655

Phase 3, Recruiting
Active & Responsive

An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.

for
Stomatitis
Location: Knoxville TN, Athens GA, Lexington KY, Elizabethtown KY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07357597

Recruiting
Active & Responsive

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

for
Heart Failure With Preserved Ejection Fraction,
Location: Powell TN, Oak Ridge TN, Asheville NC, Lenoir NC,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07037459

Phase 3, Recruiting
Active & Responsive

Daily Eating Patterns for Total Health Study

for
Obesity
Location: Knoxville TN
Sponsor: The University of Tennessee, Knoxville

Sex: All

Age: 25 - 60

Code: NCT06455995

Recruiting
Active & Responsive

Early Childhood Dietary Assessment Study

for
Dietary Assessment
Location: Knoxville TN
Sponsor: The University of Tennessee, Knoxville

Sex: All

Age: 2 - 5

Code: NCT07227272

Recruiting
Active & Responsive

ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

for
Autosomal Dominant Polycystic Kidney Disease
Location: Knoxville TN, Chattanooga TN, Atlanta GA,
Sponsor: Calico Life Sciences LLC

Sex: All

Age: 18 - 55

Code: NCT06902558

Phase 2, Recruiting
Active & Responsive

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

for
Macular Degeneration, Age-Related Macular Degeneration,
Location: Knoxville TN, Asheville NC, Johnson City TN, Hixson TN,
Sponsor: EyeBiotech Ltd.

Sex: All

Age: 50+

Code: NCT07496567

Phase 2, Phase 3, Recruiting
Active & Responsive

A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)

for
Diabetic Retinopathy, Macular Edema
Location: Knoxville TN, Johnson City TN, Charleston WV,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07705555

Phase 3, Recruiting
Active & Responsive

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for
PIK3CA Mutation, HER2- Negative Breast Cancer,
Location: Knoxville TN, Atlanta GA, Nashville TN, Indianapolis IN,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06982521

Phase 3, Recruiting
Active & Responsive

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

for
Cardiovascular Disease
Location: Oak Ridge TN, Chattanooga TN, Cumming GA, Gantt SC,
Sponsor: Amgen

Sex: All

Age: 50 - 70+

Code: NCT07136012

Phase 3, Recruiting

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: Corbin KY, Johns Creek GA, Lexington KY, Decatur GA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06058377

Phase 3, Recruiting