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Paid Clinical Trials Knoxville

Discover 213 paid clinical trials in Knoxville, Tennessee. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for
Stage I Mixed Cell Type Kidney Wilms Tumor,
Location: Knoxville TN, Chattanooga TN, Greenville SC,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 30

Code: NCT06401330

Phase3, Recruiting

A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

for
Rhabdomyosarcoma
Location: Knoxville TN, Asheville NC, Atlanta GA, Nashville TN,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 50

Code: NCT07466316

Phase3, Recruiting

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for
Ganglioneuroblastoma, Ganglioneuroblastoma, Nodular,
Location: Knoxville TN, Asheville NC, Greenville SC, Lexington KY,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 30

Code: NCT03126916

Phase3, Recruiting

Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia

for
Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia
Location: Knoxville TN, Atlanta GA, Nashville TN, Louisville KY,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 25

Code: NCT07022678

Phase3, Recruiting

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

for
Down Syndrome, Recurrent B Acute Lymphoblastic Leukemia
Location: Knoxville TN, Asheville NC, Greenville SC, Lexington KY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 1 - 30

Code: NCT04546399

Phase2, Recruiting

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A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

for
Malignant Glioma
Location: Knoxville TN, Greenville SC, Lexington KY, Atlanta GA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 1 - 21

Code: NCT05099003

Phase1, Phase2, Recruiting

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

for
B Acute Lymphoblastic Leukemia
Location: Knoxville TN, Asheville NC, Greenville SC, Lexington KY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 1 - 46

Code: NCT06124157

Phase2, Recruiting

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

for
Recurrent Langerhans Cell Histiocytosis,
Location: Knoxville TN, Asheville NC, Greenville SC, Lexington KY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 22

Code: NCT05828069

Phase2, Recruiting

A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Knoxville TN, Greenville SC, Lexington KY, Atlanta GA,
Sponsor: Children's Oncology Group

Sex: All

Age: 15 - 20

Code: NCT06410209

Phase2, Recruiting

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

for
B Acute Lymphoblastic Leukemia Associated With Down Syndrome,
Location: Knoxville TN, Greenville SC, Atlanta GA, Nashville TN,
Sponsor: Children's Oncology Group

Sex: All

Age: 6 - 39

Code: NCT05702645

Recruiting

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for
Low Grade Astrocytoma, Low Grade Glioma,
Location: Knoxville TN, Greenville SC, Lexington KY, Atlanta GA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 2 - 21

Code: NCT04166409

Phase3, Recruiting

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for
B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma,
Location: Knoxville TN, Asheville NC, Chattanooga TN,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 25

Code: NCT03959085

Phase3, Recruiting

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for
Embryonal Rhabdomyosarcoma,
Location: Knoxville TN, Greenville SC, Lexington KY, Atlanta GA,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT05304585

Phase3, Recruiting

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

for
Anaplastic Kidney Wilms Tumor, Recurrent Kidney Wilms Tumor,
Location: Knoxville TN, Asheville NC, Greenville SC, Lexington KY,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 30

Code: NCT04322318

Phase2, Recruiting

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for
Childhood Medulloblastoma
Location: Knoxville TN, Greenville SC, Atlanta GA, Charlotte NC,
Sponsor: Children's Oncology Group

Sex: All

Age: 4 - 21

Code: NCT05382338

Phase3, Recruiting

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Knoxville TN, Asheville NC, Greenville SC, Lexington KY,
Sponsor: PedAL BCU, LLC

Sex: All

Age: 0 - 22

Code: NCT04726241

Phase1, Phase2, Recruiting

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

for
Childhood Extracranial Germ Cell Tumor,
Location: Knoxville TN, Asheville NC, Chattanooga TN, Seneca SC,
Sponsor: Children's Oncology Group

Sex: All

Age: 0+

Code: NCT03067181

Phase3, Recruiting

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for
Central Nervous System Nongerminomatous Germ Cell Tumor,
Location: Knoxville TN, Greenville SC, Lexington KY, Atlanta GA,
Sponsor: Children's Oncology Group

Sex: All

Age: 3 - 29

Code: NCT04684368

Phase2, Recruiting

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

for
Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Location: Knoxville TN, Asheville NC, Chattanooga TN,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 5 - 60

Code: NCT05675410

Phase3, Recruiting

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for
Ganglioneuroblastoma, Nodular, Neuroblastoma
Location: Knoxville TN, Asheville NC, Greenville SC, Lexington KY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 30

Code: NCT06172296

Phase3, Recruiting