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Paid Clinical Trials Knoxville

Discover 213 paid clinical trials in Knoxville, Tennessee. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

for
Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma,
Location: Knoxville TN, Lexington KY, Atlanta GA, Nashville TN,
Sponsor: Sameek Roychowdhury

Sex: All

Age: 18+

Code: NCT06906562

Phase 2, Recruiting

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

for
Advanced Melanoma
Location: Knoxville TN, Greenville SC, Spartanburg SC,
Sponsor: Immunocore Ltd

Sex: All

Age: 18+

Code: NCT06112314

Phase 3, Recruiting

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for
Advanced Melanoma
Location: Knoxville TN, Atlanta GA, Louisville KY, Chapel Hill NC,
Sponsor: Replimune, Inc.

Sex: All

Age: 12+

Code: NCT06264180

Phase 3, Recruiting

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Carcinoma, Non-Small-Cell Lung
Location: Knoxville TN, Chattanooga TN, Atlanta GA, Nashville TN,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06667076

Phase 2, Recruiting

DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer (epNEC) to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

for
Extrapulmonary Neuroendocrine Cancer (epNEC)
Location: Knoxville TN, Atlanta GA, Nashville TN, St Louis MO,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT07544654

Phase 3, Recruiting

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Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

for
Pancreatic Neoplasm
Location: Knoxville TN, Greenville SC, Atlanta GA, Nashville TN,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 50 - 70+

Code: NCT04239573

Recruiting

E-Mindfulness Approaches for Living After Breast Cancer

for
Breast Cancer, Depression
Location: Knoxville TN, Seneca SC, Easley SC, Greenville SC,
Sponsor: NRG Oncology

Sex: All

Age: 18 - 50

Code: NCT06748222

Phase 3, Recruiting

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

for
Leukemia, Myeloid, Acute
Location: Knoxville TN, Lexington KY, Nashville TN, Charlotte NC,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06852222

Phase 3, Recruiting

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Knoxville TN, Shelby NC, Elizabethtown KY, Gastonia NC,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06532279

Phase 2, Recruiting

ColoCare Study - Colorectal Cancer Cohort

for
Colorectal Cancer
Location: Knoxville TN, St Louis MO, Tampa FL, Salt Lake City UT,
Sponsor: University of Utah

Sex: All

Age: 18 - 70+

Code: NCT02328677

Recruiting

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

for
Retroperitoneal Sarcoma, Liposarcoma, Leiomyosarcoma
Location: Knoxville TN, Atlanta GA, Nashville TN, Charlotte NC,
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All

Age: 18+

Code: NCT04031677

Phase 3, Recruiting

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for
Triple Negative Breast Cancer
Location: Knoxville TN, Greenville SC, Spartanburg SC, Athens GA,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT05633654

Phase 3, Recruiting

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for
Locally Advanced Lung Non-Small Cell Carcinoma,
Location: Knoxville TN, Dalton GA, Greenville SC, Forest City NC,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05624996

Phase 3, Recruiting

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

for
Metastatic Malignant Neoplasm in the Liver,
Location: Knoxville TN, Alcoa TN, Corbin KY, London KY, Seneca SC,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05040360

Phase 2, Recruiting

Evaluating Health Outcomes of AI-Based Fitness Wearables and App Programs in Older Adults Living Alone With Cognitive Decline

for
Older Adults With Cognitive Decline, Older Adults,
Location: Knoxville TN
Sponsor: The University of Tennessee, Knoxville

Sex: All

Age: 65+

Code: NCT07207993

Recruiting

Pulmonary Hypertension Association Registry

for
Pulmonary Arterial Hypertension,
Location: Knoxville TN, Anderson SC, Atlanta GA, Nashville TN,
Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All

Age: 0+

Code: NCT04071327

Recruiting

Continuous Dual Aspiration Technique With Zoom System for Stroke

for
Ischemic Stroke, Acute Stroke
Location: Knoxville TN, Greenville SC, Marietta GA, Huntsville AL,
Sponsor: Imperative Care, Inc.

Sex: All

Age: 18+

Code: NCT07491952

Recruiting

Clinical Trial Protocol: Alzheimer's Dementia Underlying Encephalopathy

for
Alzheimer Dementia, Alzheimer Disease,
Location: Knoxville TN, Oak Ridge TN, Lenoir City TN,
Sponsor: Covenant Health, US

Sex: All

Age: 60 - 70+

Code: NCT07222280

Recruiting

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for
Intracerebral Hemorrhage, Atrial Fibrillation
Location: Knoxville TN, Greenville SC, Marietta GA, Lexington KY,
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT03907046

Phase 3, Recruiting

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

for
Renal Cell Carcinoma
Location: Knoxville TN, Charlotte NC, Baltimore MD, Omaha NE,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07227402

Phase 3, Recruiting