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Paid Clinical Trials Knoxville

Discover 213 paid clinical trials in Knoxville, Tennessee. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Knoxville TN, Shelby NC, Elizabethtown KY, Gastonia NC,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06532279

Phase2, Recruiting

ColoCare Study - Colorectal Cancer Cohort

for
Colorectal Cancer
Location: Knoxville TN, St Louis MO, Tampa FL, Salt Lake City UT,
Sponsor: University of Utah

Sex: All

Age: 18 - 70+

Code: NCT02328677

Recruiting

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia,
Location: Knoxville TN, Seneca SC, Easley SC, Greenville SC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 59

Code: NCT05554406

Phase2, Recruiting

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Knoxville TN, Seneca SC, Easley SC, Greenville SC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 59

Code: NCT05554393

Phase2, Recruiting

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

for
Retroperitoneal Sarcoma, Liposarcoma, Leiomyosarcoma
Location: Knoxville TN, Atlanta GA, Nashville TN, Charlotte NC,
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All

Age: 18+

Code: NCT04031677

Phase3, Recruiting

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Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for
Triple Negative Breast Cancer
Location: Knoxville TN, Spartanburg SC, Athens GA, Marietta GA,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT05633654

Phase3, Recruiting

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for
Advanced Esophageal Adenocarcinoma,
Location: Knoxville TN, Johns Creek GA, Atlanta GA, Decatur GA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06203600

Phase2, Phase3, Recruiting

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Knoxville TN, Seneca SC, Easley SC, Greenville SC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06317649

Phase2, Recruiting

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for
Acute Myeloid Leukemia,
Location: Knoxville TN, Seneca SC, Easley SC, Greenville SC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05564390

Phase2, Recruiting

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for
Locally Advanced Lung Non-Small Cell Carcinoma,
Location: Knoxville TN, Dalton GA, Greenville SC, Forest City NC,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT05624996

Phase3, Recruiting

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

for
Metastatic Malignant Neoplasm in the Liver,
Location: Knoxville TN, Alcoa TN, Corbin KY, London KY, Seneca SC,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05040360

Phase2, Recruiting

Evaluating Health Outcomes of AI-Based Fitness Wearables and App Programs in Older Adults Living Alone With Cognitive Decline

for
Older Adults With Cognitive Decline, Older Adults,
Location: Knoxville TN
Sponsor: The University of Tennessee, Knoxville

Sex: All

Age: 65+

Code: NCT07207993

Recruiting

Pulmonary Hypertension Association Registry

for
Pulmonary Arterial Hypertension,
Location: Knoxville TN, Anderson SC, Atlanta GA, Nashville TN,
Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All

Age: 0+

Code: NCT04071327

Recruiting

Clinical Trial Protocol: Alzheimer's Dementia Underlying Encephalopathy

for
Alzheimer Dementia, Alzheimer Disease,
Location: Knoxville TN, Oak Ridge TN, Lenoir City TN,
Sponsor: Covenant Health, US

Sex: All

Age: 60 - 70+

Code: NCT07222280

Recruiting

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for
Intracerebral Hemorrhage, Atrial Fibrillation
Location: Knoxville TN, Greenville SC, Marietta GA, Lexington KY,
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT03907046

Phase3, Recruiting

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

for
Non-small Cell Lung Cancer
Location: Knoxville TN, Chattanooga TN, Nashville TN,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06077760

Phase3, Recruiting

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

for
Renal Cell Carcinoma
Location: Knoxville TN, Charlotte NC, Baltimore MD, Omaha NE,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07227402

Phase3, Recruiting

A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)

for
Bladder Cancer
Location: Knoxville TN, Cincinnati OH, Raleigh NC, Germantown TN,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07419295

Phase3, Recruiting

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

for
Basal Ganglia Germinoma, Diabetes Insipidus, Germinoma,
Location: Knoxville TN, Greenville SC, Atlanta GA, Nashville TN,
Sponsor: Children's Oncology Group

Sex: All

Age: 3 - 29

Code: NCT06368817

Phase2, Recruiting

A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

for
Cardiovascular Disorder, Classic Hodgkin Lymphoma,
Location: Knoxville TN, Atlanta GA, Winston-Salem NC,
Sponsor: Children's Oncology Group

Sex: All

Age: 7+

Code: NCT05705531

Recruiting