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Paid Clinical Trials Knoxville

Discover 213 paid clinical trials in Knoxville, Tennessee. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

for
HER2-positive Gastric Cancer,
Location: Knoxville TN, Marietta GA, Louisville KY, Charleston WV,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06764875

Phase 3, Recruiting

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

for
Overweight, Prediabetic State, Prehypertension,
Location: Knoxville TN, Dalton GA, Mauldin SC, Decatur GA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07794579

Phase 3, Recruiting

A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

for
Weight Management
Location: Knoxville TN, Woodstock GA, Gaffney SC, Franklin TN,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07667803

Phase 3, Recruiting

Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design

for
Fibromyalgia
Location: Knoxville TN, Norcross GA, Marietta GA, Atlanta GA,
Sponsor: Axsome Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07398417

Phase 3, Recruiting

A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

for
Clostridoides Difficile Associated Disease
Location: Knoxville TN, Spartanburg SC, Decatur GA, Atlanta GA,
Sponsor: Pfizer

Sex: All

Age: 65+

Code: NCT07282665

Phase 3, Recruiting

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Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

for
Breast Cancer, Locally Advanced Breast Cancer,
Location: Knoxville TN, Marietta GA, Nashville TN,
Sponsor: Olema Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07085767

Phase 3, Recruiting

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

for
High Risk Cardiovascular Disease, Hypertension,
Location: Knoxville TN, Chattanooga TN, Greenville SC, Greer SC,
Sponsor: Alnylam Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07181109

Phase 3, Recruiting

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

for
Endometrial Cancer, Malignant Solid Tumour
Location: Knoxville TN, Cincinnati OH, Roanoke VA, Pinehurst NC,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT07044336

Phase 3, Recruiting

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for
Cardiovascular Disease
Location: Knoxville TN, Morristown TN, Asheville NC,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07000357

Phase 3, Recruiting

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

for
Chronic Obstructive Pulmonary Disease (COPD)
Location: Knoxville TN, Anderson SC, Spartanburg SC, Gaffney SC,
Sponsor: AstraZeneca

Sex: All

Age: 40 - 70+

Code: NCT06878261

Phase 3, Recruiting

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for
Heart Failure and Impaired Kidney Function
Location: Knoxville TN, Asheville NC, Tullahoma TN, Tucker GA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06307652

Phase 3, Recruiting

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

for
Chronic Kidney Disease and Hypertension
Location: Knoxville TN, Chattanooga TN, Atlanta GA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06742723

Phase 3, Recruiting

A Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) and Irritable Bowel Syndrome - Mixed (IBS-M)

for
Irritable Bowel Syndrome
Location: Knoxville TN, Kingsport TN, Johnson City TN,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18 - 70+

Code: NCT07519395

Phase 2, Recruiting

A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)

for
Primary Membranous Nephropathy
Location: Knoxville TN, Nashville TN, Huntsville AL,
Sponsor: Biogen

Sex: All

Age: 18 - 70+

Code: NCT06962800

Phase 3, Recruiting

A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)

for
Immunoglobulin A Nephropathy (IgAN)
Location: Knoxville TN, Detroit MI, Gainesville FL, Brookhaven MS,
Sponsor: Biogen

Sex: All

Age: 18+

Code: NCT06935357

Phase 3, Recruiting

Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

for
AMI Cardiogenic Shock
Location: Knoxville TN, Cincinnati OH, Jonesboro AR,
Sponsor: Abiomed Inc.

Sex: All

Age: 18+

Code: NCT06964685

Recruiting

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for
Aortic Stenosis, Calcific, Aortic Valve Stenosis
Location: Knoxville TN, Atlanta GA, Nashville TN, Huntsville AL,
Sponsor: Edwards Lifesciences

Sex: All

Age: 65+

Code: NCT04889872

Recruiting

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for
Aortic Stenosis, Coronary Artery Disease, Coronary Stenosis
Location: Knoxville TN, Kingsport TN, Gainesville GA, Atlanta GA,
Sponsor: University of British Columbia

Sex: All

Age: 0+

Code: NCT04634240

Recruiting

A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

for
Multiple Sclerosis Spasticity
Location: Knoxville TN, Cincinnati OH, Birmingham AL, Columbus OH,
Sponsor: Celgene

Sex: All

Age: 18 - 70

Code: NCT06782490

Phase 2, Recruiting

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

for
Relapsing Multiple Sclerosis
Location: Knoxville TN, Greenville SC, Cincinnati OH,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 40 - 70

Code: NCT06846281

Phase 3, Recruiting