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Paid Clinical Trials Knoxville

Discover 213 paid clinical trials in Knoxville, Tennessee. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design

for
Fibromyalgia
Location: Knoxville TN, Norcross GA, Marietta GA, Atlanta GA,
Sponsor: Axsome Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07398417

Phase3, Recruiting

A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

for
Clostridoides Difficile Associated Disease
Location: Knoxville TN, Spartanburg SC, Decatur GA, Atlanta GA,
Sponsor: Pfizer

Sex: All

Age: 65+

Code: NCT07282665

Phase3, Recruiting

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

for
High Risk Cardiovascular Disease, Hypertension,
Location: Knoxville TN, Chattanooga TN, Greenville SC, Greer SC,
Sponsor: Alnylam Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07181109

Phase3, Recruiting

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

for
Endometrial Cancer, Malignant Solid Tumour
Location: Knoxville TN, Cincinnati OH, Roanoke VA, Pinehurst NC,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT07044336

Phase3, Recruiting

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for
Cardiovascular Disease
Location: Knoxville TN, Morristown TN, Asheville NC,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07000357

Phase3, Recruiting

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A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

for
Chronic Obstructive Pulmonary Disease (COPD)
Location: Knoxville TN, Anderson SC, Spartanburg SC, Gaffney SC,
Sponsor: AstraZeneca

Sex: All

Age: 40 - 70+

Code: NCT06878261

Phase3, Recruiting

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for
Heart Failure and Impaired Kidney Function
Location: Knoxville TN, Asheville NC, Tullahoma TN, Tucker GA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06307652

Phase3, Recruiting

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

for
Chronic Kidney Disease and Hypertension
Location: Knoxville TN, Chattanooga TN, Atlanta GA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06742723

Phase3, Recruiting

A Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) and Irritable Bowel Syndrome - Mixed (IBS-M)

for
Irritable Bowel Syndrome
Location: Knoxville TN, Kingsport TN, Johnson City TN,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18 - 70+

Code: NCT07519395

Phase2, Recruiting

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

for
Cardiovascular Disease and Lipoprotein(a)
Location: Powell TN, Atlanta GA, Nashville TN, Huntsville AL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07517263

Phase3, Recruiting

A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)

for
Primary Membranous Nephropathy
Location: Knoxville TN, Nashville TN, Huntsville AL,
Sponsor: Biogen

Sex: All

Age: 18 - 70+

Code: NCT06962800

Phase3, Recruiting

A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)

for
Immunoglobulin A Nephropathy (IgAN)
Location: Knoxville TN, Detroit MI, Gainesville FL, Brookhaven MS,
Sponsor: Biogen

Sex: All

Age: 18+

Code: NCT06935357

Phase3, Recruiting

Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

for
AMI Cardiogenic Shock
Location: Knoxville TN, Cincinnati OH, Jonesboro AR,
Sponsor: Abiomed Inc.

Sex: All

Age: 18+

Code: NCT06964685

Recruiting

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for
Aortic Stenosis, Calcific, Aortic Valve Stenosis
Location: Knoxville TN, Atlanta GA, Nashville TN, Huntsville AL,
Sponsor: Edwards Lifesciences

Sex: All

Age: 65+

Code: NCT04889872

Recruiting

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for
Aortic Stenosis, Coronary Artery Disease, Coronary Stenosis
Location: Knoxville TN, Kingsport TN, Gainesville GA, Atlanta GA,
Sponsor: University of British Columbia

Sex: All

Age: 0+

Code: NCT04634240

Recruiting

A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

for
Multiple Sclerosis Spasticity
Location: Knoxville TN, Cincinnati OH, Birmingham AL, Columbus OH,
Sponsor: Celgene

Sex: All

Age: 18 - 70

Code: NCT06782490

Phase2, Recruiting

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

for
Relapsing Multiple Sclerosis
Location: Knoxville TN, Greenville SC, Cincinnati OH,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 40 - 70

Code: NCT06846281

Phase3, Recruiting

Evaluation of Safety and Efficacy of Morpheus8 Applicator for the Treatment of Focal Hyperhidrosis of the Axillae Using Radio Frequency

for
Hyperhidrosis Primary Focal Axilla
Location: Knoxville TN, Dallas TX
Sponsor: InMode MD Ltd.

Sex: All

Age: 18+

Code: NCT05860972

Recruiting

Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

for
Macular Telangiectasia Type 2 (MacTel)
Location: Knoxville TN, Atlanta GA, Cincinnati OH, Cleveland OH,
Sponsor: Neurotech Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06971939

Recruiting

Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab

for
Relapsing Multiple Sclerosis
Location: Knoxville TN, Greenville SC, Atlanta GA, Charlotte NC,
Sponsor: TG Therapeutics, Inc.

Sex: All

Age: 18 - 65

Code: NCT05877963

Phase3, Recruiting