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Paid Clinical Trials Knoxville

Discover 213 paid clinical trials in Knoxville, Tennessee. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for
Melanoma
Location: Knoxville TN, Asheville NC, Chattanooga TN, Athens GA,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06246916

Phase3, Recruiting

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

for
Non-small Cell Lung Cancer
Location: Knoxville TN, Hendersonville NC, Nashville TN,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06712316

Phase2, Phase3, Recruiting

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

for
Metastatic Non Small Cell Lung Cancer
Location: Knoxville TN, Louisville KY, Cincinnati OH,
Sponsor: Iovance Biotherapeutics, Inc.

Sex: All

Age: 18 - 70

Code: NCT04614103

Phase2, Recruiting

Biodistribution and Kinetics of 18F-AraG in Non-Small Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Knoxville TN
Sponsor: University of Tennessee

Sex: All

Age: 21+

Code: NCT04052412

Phase1, Recruiting

Fasting Mimicking Diet in Chemotherapy of Gynecologic Malignancies

for
Cancer, Ovarian, Chemotherapy Effect, Calorie Deficiency,
Location: Knoxville TN
Sponsor: L-Nutra Inc

Sex: Female

Age: 35 - 70

Code: NCT06376604

Recruiting

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ESP Block vs Control for Pain Control Following Percutaneous Nephrolithotomy

for
Nephrolithotomy, Percutaneous
Location: Knoxville TN
Sponsor: University of Tennessee Medical Center

Sex: All

Age: 18+

Code: NCT05024344

Recruiting

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

for
Non-Muscle Invasive Bladder Cancer
Location: Knoxville TN, Nashville TN, Charlotte NC, Raleigh NC,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06319820

Phase3, Recruiting

Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC

for
Carcinoma, Non-Small-Cell Lung, Lung Cancer (NSCLC),
Location: Knoxville TN, Athens GA, Huntsville AL, New Lenox IL,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07489066

Phase2, Recruiting

REVASC-PAD: REstricted VASCular Exercise for Peripheral Arterial Disease - A Feasibility Study at University of Tennessee Medical Center

for
Peripheral Arterial Disease
Location: Knoxville TN
Sponsor: University of Tennessee Graduate School of Medicine

Sex: All

Age: 18+

Code: NCT07223437

Recruiting

A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer,
Location: Knoxville TN, Nashville TN, St Louis MO,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07154290

Phase2, Recruiting

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

for
Head and Neck Squamous Cell Carcinoma (HNSCC)
Location: Knoxville TN, Atlanta GA, Nashville TN, Louisville KY,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06769698

Phase2, Recruiting

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

for
Ovarian Neoplasms, Ovarian Cancer
Location: Knoxville TN, Atlanta GA, Nashville TN, Cincinnati OH,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT07318558

Phase3, Recruiting

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

for
Extensive-stage Small-cell Lung Cancer
Location: Knoxville TN, Atlanta GA, Elizabethtown KY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06712355

Phase3, Recruiting

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

for
Cervical Cancer
Location: Knoxville TN, Atlanta GA, Columbus OH, Savannah GA,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT07216703

Phase3, Recruiting

Robotic Versus Open Ventral Hernia Repair

for
Ventral Hernia
Location: Knoxville TN, Greenville SC, Cleveland OH,
Sponsor: Lucas Beffa

Sex: All

Age: 18+

Code: NCT05472987

Recruiting

Improved Outcomes With Pre-Procedure Shockwave IVL of Common Femoral Artery Access Site Prior to Large Bore Access and Pre-Closure

for
Aortic Stenosis
Location: Knoxville TN
Sponsor: University of Tennessee Graduate School of Medicine

Sex: All

Age: 18+

Code: NCT07205068

Recruiting

AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE

for
Hernia
Location: Knoxville TN, Columbus OH, Wilmington NC,
Sponsor: Tissium

Sex: All

Age: 22+

Code: NCT07277946

Recruiting

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

for
Pancreatic Neuroendocrine Tumor (pNET),
Location: Knoxville TN, Lexington KY, Nashville TN, Birmingham AL,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT06943755

Phase2, Phase3, Recruiting

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

for
Small Cell Lung Cancer Extensive Stage
Location: Knoxville TN, Nashville TN, Edgewood KY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07227597

Phase1, Phase2, Recruiting

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

for
Hepatocellular Carcinoma, Biliary Tract Cancer
Location: Knoxville TN, Germantown TN, Pittsburgh PA,
Sponsor: Replimune Inc.

Sex: All

Age: 18+

Code: NCT05733598

Phase2, Recruiting