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Paid Clinical Trials Knoxville

Discover 213 paid clinical trials in Knoxville, Tennessee. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for
Advanced Non-Small Cell Lung Cancer, Non-Small Cell Lung Cancer,
Location: Knoxville TN, Chattanooga TN, Lebanon TN,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07222566

Phase 3, Recruiting

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

for
Metastatic Uveal Melanoma
Location: Knoxville TN, Atlanta GA, Nashville TN, Durham NC,
Sponsor: Replimune Inc.

Sex: All

Age: 0+

Code: NCT06581406

Phase 2, Phase 3, Recruiting

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for
Melanoma
Location: Knoxville TN, Asheville NC, Chattanooga TN, Athens GA,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06246916

Phase 3, Recruiting

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer (ROSETTA Lung-02)

for
Non-small Cell Lung Cancer
Location: Knoxville TN, Hendersonville NC, Marietta GA,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06712316

Phase 2, Phase 3, Recruiting

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

for
Metastatic Non Small Cell Lung Cancer
Location: Knoxville TN, Louisville KY, Cincinnati OH,
Sponsor: Iovance Biotherapeutics, Inc.

Sex: All

Age: 18 - 70

Code: NCT04614103

Phase 2, Recruiting

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Biodistribution and Kinetics of 18F-AraG in Non-Small Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Knoxville TN
Sponsor: University of Tennessee

Sex: All

Age: 21+

Code: NCT04052412

Phase 1, Recruiting

Fasting Mimicking Diet in Chemotherapy of Gynecologic Malignancies

for
Cancer, Ovarian, Chemotherapy Effect, Calorie Deficiency,
Location: Knoxville TN
Sponsor: L-Nutra Inc

Sex: Female

Age: 35 - 70

Code: NCT06376604

Recruiting

ESP Block vs Control for Pain Control Following Percutaneous Nephrolithotomy

for
Nephrolithotomy, Percutaneous
Location: Knoxville TN
Sponsor: University of Tennessee Medical Center

Sex: All

Age: 18+

Code: NCT05024344

Recruiting

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

for
Non-Muscle Invasive Bladder Cancer
Location: Knoxville TN, Nashville TN, Charlotte NC, Raleigh NC,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06319820

Phase 3, Recruiting

Whole Body Metabolic Activity as a Reflection of Tumor Metabolic Dysregulation and a Predictor of Treatment Response in Ovarian Cancer

for
Epithelial Ovarian Cancer
Location: Knoxville TN
Sponsor: University of Tennessee Graduate School of Medicine

Sex: Female

Age: 18+

Code: NCT07764133

Recruiting

Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC

for
Carcinoma, Non-Small-Cell Lung, Lung Cancer (NSCLC),
Location: Knoxville TN, Athens GA, Huntsville AL, New Lenox IL,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07489066

Phase 2, Recruiting

REVASC-PAD: REstricted VASCular Exercise for Peripheral Arterial Disease - A Feasibility Study at University of Tennessee Medical Center

for
Peripheral Arterial Disease
Location: Knoxville TN
Sponsor: University of Tennessee Graduate School of Medicine

Sex: All

Age: 18+

Code: NCT07223437

Recruiting

A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer,
Location: Knoxville TN, Nashville TN, Birmingham AL, St Louis MO,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07154290

Phase 2, Recruiting

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

for
Head and Neck Squamous Cell Carcinoma (HNSCC)
Location: Knoxville TN, Atlanta GA, Nashville TN, Louisville KY,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06769698

Phase 2, Recruiting

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

for
Ovarian Neoplasms, Ovarian Cancer
Location: Knoxville TN, Atlanta GA, Nashville TN, Cincinnati OH,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT07318558

Phase 3, Recruiting

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

for
Extensive-stage Small-cell Lung Cancer
Location: Knoxville TN, Atlanta GA, Elizabethtown KY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT06712355

Phase 3, Recruiting

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

for
Cervical Cancer
Location: Knoxville TN, Atlanta GA, Birmingham AL, Columbus OH,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT07216703

Phase 3, Recruiting

Robotic Versus Open Ventral Hernia Repair

for
Ventral Hernia
Location: Knoxville TN, Greenville SC, Cleveland OH,
Sponsor: Lucas Beffa

Sex: All

Age: 18+

Code: NCT05472987

Recruiting

Improved Outcomes With Pre-Procedure Shockwave IVL of Common Femoral Artery Access Site Prior to Large Bore Access and Pre-Closure

for
Aortic Stenosis
Location: Knoxville TN
Sponsor: University of Tennessee Graduate School of Medicine

Sex: All

Age: 18+

Code: NCT07205068

Recruiting

AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE

for
Hernia
Location: Knoxville TN, Lexington KY, Durham NC, Columbus OH,
Sponsor: Tissium

Sex: All

Age: 22+

Code: NCT07277946

Recruiting