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A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma
A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer
A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia
Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)
A Study of Raludotatug Deruxtecan With or Without Bevacizumab as First-Line Maintenance Treatment in Non-HRD-Positive Advanced Ovarian Cancer (MK-5909-006, (ENGOT-ov102/GOG-3141/ REJOICE-Ovarian 04)
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
Clinical trials in Tyler, TX: what is studied
Cancer. Cancer research makes up a large share of the studies in Tyler, most of it through Texas Oncology and the UT Health East Texas HOPE Cancer Center. Studies often cover common cancers such as lung cancer, breast cancer, and colorectal cancer, along with gynecologic and blood cancers; see our oncology clinical trials page.
Digestive diseases. Tyler Research Institute is a dedicated research site, and many of its studies are for people with Crohn's disease and ulcerative colitis.
Our guide to Crohn's treatment explains what is approved today.
Heart, metabolic, and other conditions. Local cardiology practices take part in heart failure and other heart studies, and studies in obesity, type 2 diabetes, eye disease, and asthma also recruit in the city. Our weight loss clinical trials page lists studies of new weight loss medicines.
Do clinical trials in Tyler pay?
Some studies offer compensation for time and travel, and study related care is typically provided at no cost to participants. Compensation varies by trial and is always described during the informed consent process before you agree to anything. The institutional review board (IRB) that oversees each study reviews the amount and timing of any payment, and FDA guidance says payment should build up as the study goes on rather than depend on finishing it. Many studies at least cover travel, which matters for people who drive in from smaller towns across East Texas.
Our guide explains how much clinical trials pay and how payment is decided.
How to join a clinical trial in Tyler
- Identify your trial. Use the filters on this page to narrow the list by condition or phase, or search a diagnosis such as Crohn's disease or lung cancer.
- Check the location. Each study lists the sites where it recruits, so confirm it has a site in Tyler and not only in Dallas or Houston.
- Explore study details. Read the eligibility criteria and, where listed, the number of visits and how long the study lasts before applying.
- Complete the health profile. Click "See if you qualify" to begin the 5-step application. Have ready your diagnosis and when it was made, the medicines you take, and any recent test results.
- Submit the application. A clinical trial coordinator reviews it and contacts you to discuss next steps. Nothing is decided until informed consent, and participation is voluntary at every step.
Our guide to finding clinical trials near you covers each step in more detail.
Do I need health insurance to join a clinical trial?
Not always. Study related care, including the study medicine and the visits and tests the protocol requires, is typically provided at no cost to participants. Routine care you would receive anyway may be billed to your insurance, and the study team explains what is covered before you sign anything. Our guide to insurance for clinical trials covers the details.
Clinical trials near Tyler and across Texas
If nothing in Tyler fits, our Dallas clinical trials page lists the larger research programs about 100 miles west, and our Dallas clinical trials guide explains the city's main institutions. Shreveport, about 100 miles east in Louisiana, has its own page, and studies across the state are on our Texas clinical trials page.