A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors
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Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)
A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
A Study of APG-115 Alone or Combined With Azacitidine in Patients With AML, CMML, or MDS
Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL
A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer
A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).
Clinical trials in Tyler, TX: what is studied
Cancer. Cancer research makes up a large share of the studies in Tyler, most of it through Texas Oncology and the UT Health East Texas HOPE Cancer Center. Studies often cover common cancers such as lung cancer, breast cancer, and colorectal cancer, along with gynecologic and blood cancers; see our oncology clinical trials page.
Digestive diseases. Tyler Research Institute is a dedicated research site, and many of its studies are for people with Crohn's disease and ulcerative colitis.
Our guide to Crohn's treatment explains what is approved today.
Heart, metabolic, and other conditions. Local cardiology practices take part in heart failure and other heart studies, and studies in obesity, type 2 diabetes, eye disease, and asthma also recruit in the city. Our weight loss clinical trials page lists studies of new weight loss medicines.
Do clinical trials in Tyler pay?
Some studies offer compensation for time and travel, and study related care is typically provided at no cost to participants. Compensation varies by trial and is always described during the informed consent process before you agree to anything. The institutional review board (IRB) that oversees each study reviews the amount and timing of any payment, and FDA guidance says payment should build up as the study goes on rather than depend on finishing it. Many studies at least cover travel, which matters for people who drive in from smaller towns across East Texas.
Our guide explains how much clinical trials pay and how payment is decided.
How to join a clinical trial in Tyler
- Identify your trial. Use the filters on this page to narrow the list by condition or phase, or search a diagnosis such as Crohn's disease or lung cancer.
- Check the location. Each study lists the sites where it recruits, so confirm it has a site in Tyler and not only in Dallas or Houston.
- Explore study details. Read the eligibility criteria and, where listed, the number of visits and how long the study lasts before applying.
- Complete the health profile. Click "See if you qualify" to begin the 5-step application. Have ready your diagnosis and when it was made, the medicines you take, and any recent test results.
- Submit the application. A clinical trial coordinator reviews it and contacts you to discuss next steps. Nothing is decided until informed consent, and participation is voluntary at every step.
Our guide to finding clinical trials near you covers each step in more detail.
Do I need health insurance to join a clinical trial?
Not always. Study related care, including the study medicine and the visits and tests the protocol requires, is typically provided at no cost to participants. Routine care you would receive anyway may be billed to your insurance, and the study team explains what is covered before you sign anything. Our guide to insurance for clinical trials covers the details.
Clinical trials near Tyler and across Texas
If nothing in Tyler fits, our Dallas clinical trials page lists the larger research programs about 100 miles west, and our Dallas clinical trials guide explains the city's main institutions. Shreveport, about 100 miles east in Louisiana, has its own page, and studies across the state are on our Texas clinical trials page.