A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
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A Study to Compare Setidegrasib (ASP3082) With Docetaxel, in People With Non-small Cell Lung Cancer With a KRAS G12D Mutation
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC
A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
Clinical trials in Tyler, TX: what is studied
Cancer. Cancer research makes up a large share of the studies in Tyler, most of it through Texas Oncology and the UT Health East Texas HOPE Cancer Center. Studies often cover common cancers such as lung cancer, breast cancer, and colorectal cancer, along with gynecologic and blood cancers; see our oncology clinical trials page.
Digestive diseases. Tyler Research Institute is a dedicated research site, and many of its studies are for people with Crohn's disease and ulcerative colitis.
Our guide to Crohn's treatment explains what is approved today.
Heart, metabolic, and other conditions. Local cardiology practices take part in heart failure and other heart studies, and studies in obesity, type 2 diabetes, eye disease, and asthma also recruit in the city. Our weight loss clinical trials page lists studies of new weight loss medicines.
Do clinical trials in Tyler pay?
Some studies offer compensation for time and travel, and study related care is typically provided at no cost to participants. Compensation varies by trial and is always described during the informed consent process before you agree to anything. The institutional review board (IRB) that oversees each study reviews the amount and timing of any payment, and FDA guidance says payment should build up as the study goes on rather than depend on finishing it. Many studies at least cover travel, which matters for people who drive in from smaller towns across East Texas.
Our guide explains how much clinical trials pay and how payment is decided.
How to join a clinical trial in Tyler
- Identify your trial. Use the filters on this page to narrow the list by condition or phase, or search a diagnosis such as Crohn's disease or lung cancer.
- Check the location. Each study lists the sites where it recruits, so confirm it has a site in Tyler and not only in Dallas or Houston.
- Explore study details. Read the eligibility criteria and, where listed, the number of visits and how long the study lasts before applying.
- Complete the health profile. Click "See if you qualify" to begin the 5-step application. Have ready your diagnosis and when it was made, the medicines you take, and any recent test results.
- Submit the application. A clinical trial coordinator reviews it and contacts you to discuss next steps. Nothing is decided until informed consent, and participation is voluntary at every step.
Our guide to finding clinical trials near you covers each step in more detail.
Do I need health insurance to join a clinical trial?
Not always. Study related care, including the study medicine and the visits and tests the protocol requires, is typically provided at no cost to participants. Routine care you would receive anyway may be billed to your insurance, and the study team explains what is covered before you sign anything. Our guide to insurance for clinical trials covers the details.
Clinical trials near Tyler and across Texas
If nothing in Tyler fits, our Dallas clinical trials page lists the larger research programs about 100 miles west, and our Dallas clinical trials guide explains the city's main institutions. Shreveport, about 100 miles east in Louisiana, has its own page, and studies across the state are on our Texas clinical trials page.