A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
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Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
A Study Evaluating Ficerafusp Alfa (BCA101) QW in Combination With Pembrolizumab vs Alternative Ficerafusp Alfa Dosing in 1L R or M HNSCC
Lisaftoclax (APG-2575) Combined With Azacytidine (AZA) in the Treatment of Patients With Higher-risk Myelodysplastic Syndrome (GLORA-4).
A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)
A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease
Clinical trials in Tyler, TX: what is studied
Cancer. Cancer research makes up a large share of the studies in Tyler, most of it through Texas Oncology and the UT Health East Texas HOPE Cancer Center. Studies often cover common cancers such as lung cancer, breast cancer, and colorectal cancer, along with gynecologic and blood cancers; see our oncology clinical trials page.
Digestive diseases. Tyler Research Institute is a dedicated research site, and many of its studies are for people with Crohn's disease and ulcerative colitis.
Our guide to Crohn's treatment explains what is approved today.
Heart, metabolic, and other conditions. Local cardiology practices take part in heart failure and other heart studies, and studies in obesity, type 2 diabetes, eye disease, and asthma also recruit in the city. Our weight loss clinical trials page lists studies of new weight loss medicines.
Do clinical trials in Tyler pay?
Some studies offer compensation for time and travel, and study related care is typically provided at no cost to participants. Compensation varies by trial and is always described during the informed consent process before you agree to anything. The institutional review board (IRB) that oversees each study reviews the amount and timing of any payment, and FDA guidance says payment should build up as the study goes on rather than depend on finishing it. Many studies at least cover travel, which matters for people who drive in from smaller towns across East Texas.
Our guide explains how much clinical trials pay and how payment is decided.
How to join a clinical trial in Tyler
- Identify your trial. Use the filters on this page to narrow the list by condition or phase, or search a diagnosis such as Crohn's disease or lung cancer.
- Check the location. Each study lists the sites where it recruits, so confirm it has a site in Tyler and not only in Dallas or Houston.
- Explore study details. Read the eligibility criteria and, where listed, the number of visits and how long the study lasts before applying.
- Complete the health profile. Click "See if you qualify" to begin the 5-step application. Have ready your diagnosis and when it was made, the medicines you take, and any recent test results.
- Submit the application. A clinical trial coordinator reviews it and contacts you to discuss next steps. Nothing is decided until informed consent, and participation is voluntary at every step.
Our guide to finding clinical trials near you covers each step in more detail.
Do I need health insurance to join a clinical trial?
Not always. Study related care, including the study medicine and the visits and tests the protocol requires, is typically provided at no cost to participants. Routine care you would receive anyway may be billed to your insurance, and the study team explains what is covered before you sign anything. Our guide to insurance for clinical trials covers the details.
Clinical trials near Tyler and across Texas
If nothing in Tyler fits, our Dallas clinical trials page lists the larger research programs about 100 miles west, and our Dallas clinical trials guide explains the city's main institutions. Shreveport, about 100 miles east in Louisiana, has its own page, and studies across the state are on our Texas clinical trials page.